The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ACADIA PHARMACEUTICALS INC | COM | 004225108 | 890 | 27,300 | SH | SOLE | 27,300 | 0 | 0 | ||
| ACHILLION PHARMACEUTICALS INC | COM | 00448Q201 | 80,926 | 8,207,530 | SH | SOLE | 8,207,530 | 0 | 0 | ||
| AGIOS PHARMACEUTICALS INC | COM | 00847X104 | 1,660 | 17,600 | SH | SOLE | 17,600 | 0 | 0 | ||
| AGILE THERAPEUTICS INC | COM | 00847L100 | 13,523 | 1,458,792 | SH | SOLE | 1,458,792 | 0 | 0 | ||
| AKEBIA THERAPEUTICS INC | COM | 00972D105 | 6,637 | 597,363 | SH | SOLE | 597,363 | 0 | 0 | ||
| ALKERMES PLC | SHS | G01767105 | 1,171 | 19,200 | SH | SOLE | 19,200 | 0 | 0 | ||
| AMGEN INC | COM | 031162100 | 943 | 5,900 | SH | SOLE | 5,900 | 0 | 0 | ||
| ARRAY BIOPHARMA INC | COM | 04269X105 | 10,005 | 1,357,584 | SH | SOLE | 1,357,584 | 0 | 0 | ||
| ASCENDIS PHARMA A S | SPONSORED ADR | 04351P101 | 17,760 | 1,023,652 | SH | SOLE | 1,023,652 | 0 | 0 | ||
| AURINIA PHARMACEUTICALS INC | COM | 05156V102 | 6,561 | 1,504,776 | SH | SOLE | 1,504,776 | 0 | 0 | ||
| BIOCRYST PHARMACEUTICALS | COM | 09058V103 | 62,547 | 6,926,617 | SH | SOLE | 6,926,617 | 0 | 0 | ||
| BIOGEN INC | COM | 09062X103 | 1,098 | 2,600 | SH | SOLE | 2,600 | 0 | 0 | ||
| BELLICUM PHARMACEUTICALS INC | COM | 079481107 | 23,782 | 1,026,402 | SH | SOLE | 1,026,402 | 0 | 0 | ||
| BLUEBIRD BIO INC | COM | 09609G100 | 24,200 | 200,379 | SH | SOLE | 200,379 | 0 | 0 | ||
| BIOTA PHARMACEUTIALS INC | COM | 090694100 | 3,229 | 1,403,853 | SH | SOLE | 1,403,853 | 0 | 0 | ||
| CELGENE CORP | COM | 151020104 | 1,003 | 8,700 | SH | SOLE | 8,700 | 0 | 0 | ||
| COHERUS BIOSCIENCES INC | COM | 19249H103 | 47,563 | 1,555,355 | SH | SOLE | 1,555,355 | 0 | 0 | ||
| CELLADON CORP | COM | 15117E107 | 775 | 40,900 | SH | SOLE | 40,900 | 0 | 0 | ||
| CONCERT PHARMACEUTICALS INC | COM | 206022105 | 9,996 | 660,000 | SH | SOLE | 660,000 | 0 | 0 | ||
| DICERNA PHARMACEUTICALS INC | COM | 253031108 | 58,359 | 2,428,571 | SH | SOLE | 2,428,571 | 0 | 0 | ||
| DYNAVAX TECHNOLOGIES CORP | COM NEW | 268158201 | 58,318 | 2,600,000 | SH | SOLE | 2,600,000 | 0 | 0 | ||
| DYAX CORP | COM | 26746E103 | 70,498 | 4,207,594 | SH | SOLE | 4,207,594 | 0 | 0 | ||
| AURIS MED HLDG AG | COM | H03579101 | 5,029 | 940,000 | SH | SOLE | 940,000 | 0 | 0 | ||
| JUNO THERAPEUTICS INC | COM | 48205A109 | 16,985 | 280,000 | SH | SOLE | 280,000 | 0 | 0 | ||
| KERYX BIOPHARMACEUTICALS INC | COM | 492515101 | 754 | 59,200 | SH | SOLE | 59,200 | 0 | 0 | ||
| MERRIMACK PHARMACEUTICALS IN | COM | 590328100 | 1,383 | 116,400 | SH | SOLE | 116,400 | 0 | 0 | ||
| NEWLINK GENETICS CORP | COM | 651511107 | 1,641 | 30,000 | SH | SOLE | 30,000 | 0 | 0 | ||
| NOVAVAX INC | COM | 670002104 | 11,836 | 1,431,232 | SH | SOLE | 1,431,232 | 0 | 0 | ||
| OCERA THERAPEUTICS INC | COM | 67552A108 | 1,966 | 417,476 | SH | SOLE | 417,476 | 0 | 0 | ||
| OMEROS CORP | COM | 682143102 | 16,500 | 749,000 | SH | SOLE | 749,000 | 0 | 0 | ||
| ONCOTHYREON INC | COM | 682324108 | 1,900 | 1,165,765 | SH | SOLE | 1,165,765 | 0 | 0 | ||
| OREXIGEN THERAPEUTICS INC | COM | 686164104 | 9,288 | 1,186,229 | SH | SOLE | 1,186,229 | 0 | 0 | ||
| PUMA BIOTECHNOLOGY INC | COM | 74587V107 | 732 | 3,100 | SH | SOLE | 3,100 | 0 | 0 | ||
| PROTEON THERAPEUTICS INC | COM | 74371L109 | 14,538 | 1,250,000 | SH | SOLE | 1,250,000 | 0 | 0 | ||
| PTC THERAPEUTICS INC | COM | 69366J200 | 1,570 | 25,800 | SH | SOLE | 25,800 | 0 | 0 | ||
| REGENERON PHARMACEUTICALS | COM | 75886F107 | 1,106 | 2,450 | SH | SOLE | 2,450 | 0 | 0 | ||
| REPLIGEN CORP | COM | 759916109 | 1,366 | 45,000 | SH | SOLE | 45,000 | 0 | 0 | ||
| REGULUS THERAPEUTICS INC | COM | 75915K101 | 60,826 | 3,590,688 | SH | SOLE | 3,590,688 | 0 | 0 | ||
| ROCKWELL MED INC | COM | 774374102 | 2,735 | 250,207 | SH | SOLE | 250,207 | 0 | 0 | ||
| SUCAMPO PHARMACEUTICALS INC | CL A | 864909106 | 7,002 | 450,000 | SH | SOLE | 450,000 | 0 | 0 | ||
| SCYNEXIS INC | COM | 811292101 | 6,550 | 789,097 | SH | SOLE | 789,097 | 0 | 0 | ||
| SANGAMO BIOSCIENCES INC | COM | 800677106 | 19,133 | 1,220,209 | SH | SOLE | 1,220,209 | 0 | 0 | ||
| SANGAMO BIOSCIENCES INC | COM | 800677106 | 94,080 | 6,000,000 | SH | Call | SOLE | 0 | 0 | 0 | |
| TENAX THERAPEUTICS INC | COM | 88032L100 | 8,705 | 2,670,300 | SH | SOLE | 2,670,300 | 0 | 0 | ||
| TG THERAPEUTICS INC | COM | 88322Q108 | 48,377 | 3,125,149 | SH | SOLE | 3,125,149 | 0 | 0 | ||
| TEKMIRA PHARMACEUTICALS CORP | COM NEW | 87911B209 | 47,400 | 2,714,800 | SH | SOLE | 2,714,800 | 0 | 0 | ||
| TROVAGENE INC | COM NEW | 897238309 | 4,047 | 594,200 | SH | SOLE | 594,200 | 0 | 0 | ||
| TREVENA INC | COM | 89532E109 | 8,642 | 1,325,407 | SH | SOLE | 1,325,407 | 0 | 0 | ||
| TESARO INC | COM | 881569107 | 1,349 | 23,500 | SH | SOLE | 23,500 | 0 | 0 | ||
| T2 BIOSYSTEMS INC | COM | 89853L104 | 2,142 | 138,002 | SH | SOLE | 138,002 | 0 | 0 | ||
| THERAPEUTICSMD INC | COM | 88338N107 | 10,166 | 1,680,395 | SH | SOLE | 1,680,395 | 0 | 0 | ||
| VICAL INC | COM | 925602104 | 6,637 | 7,024,274 | SH | SOLE | 7,024,274 | 0 | 0 | ||
| VERSARTIS INC | COM | 92529L102 | 4,248 | 231,267 | SH | SOLE | 231,267 | 0 | 0 | ||
| WAFERGEN BIO-SYSTEMS INC | COM PAR$ | 93041P308 | 1,157 | 255,400 | SH | SOLE | 255,400 | 0 | 0 | ||
| XENCOR INC | COM | 98401F105 | 32,929 | 2,149,423 | SH | SOLE | 2,149,423 | 0 | 0 | ||
| ZAFGEN INC | COM | 98885E103 | 29,033 | 732,960 | SH | SOLE | 732,960 | 0 | 0 | ||
| ZS PHARMA INC | COM | 98979G105 | 23,753 | 564,483 | SH | SOLE | 564,483 | 0 | 0 | ||