The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ACHILLION PHARMACEUTICALS INC | COM | 00448Q201 | 81,081 | 11,733,815 | SH | SOLE | 11,733,815 | 0 | 0 | ||
| AGILE THERAPEUTICS INC | COM | 00847L100 | 4,251 | 630,702 | SH | SOLE | 630,702 | 0 | 0 | ||
| AIMMUNE THERAPEUTICS INC | COM | 00900T107 | 20,008 | 790,200 | SH | SOLE | 790,200 | 0 | 0 | ||
| AKARI THERAPEUTICS PLC | SPONSORED ADR | 00972G108 | 6,333 | 263,921 | SH | SOLE | 263,921 | 0 | 0 | ||
| ALCOBRA LTD | SHS | M2239P109 | 11,071 | 1,832,911 | SH | SOLE | 1,832,911 | 0 | 0 | ||
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 5,065 | 63,026 | SH | SOLE | 63,026 | 0 | 0 | ||
| AMPLIPHI BIOSCIENCES CORP | COM NEW | 03211P202 | 257 | 65,100 | SH | SOLE | 65,100 | 0 | 0 | ||
| APPLIED GENETIC TECHNOL CORP | COM | 03820J100 | 1,591 | 121,100 | SH | SOLE | 121,100 | 0 | 0 | ||
| AQUINOX PHARMACEUTICALS INC | COM | 03842B101 | 21,557 | 1,532,151 | SH | SOLE | 1,532,151 | 0 | 0 | ||
| ARCA BIOPHARMA INC | COM PAR$.001 | 00211Y407 | 4,024 | 811,227 | SH | SOLE | 811,227 | 0 | 0 | ||
| ARDELYX INC | COM | 039697107 | 18,386 | 1,064,013 | SH | SOLE | 1,064,013 | 0 | 0 | ||
| ASCENDIS PHARMA A S | SPONSORED ADR | 04351P101 | 25,864 | 1,461,268 | SH | SOLE | 1,461,268 | 0 | 0 | ||
| AURIS MED HLDG AG | COM | H03579101 | 1,665 | 467,572 | SH | SOLE | 467,572 | 0 | 0 | ||
| AXOVANT SCIENCES LTD | COM | G0750W104 | 64,600 | 5,000,000 | SH | SOLE | 5,000,000 | 0 | 0 | ||
| BELLICUM PHARMACEUTICALS INC | COM | 079481107 | 4,587 | 315,704 | SH | SOLE | 315,704 | 0 | 0 | ||
| BENITEC BIOPHARMA LTD | SPONS ADR NEW | 082053307 | 864 | 140,548 | SH | SOLE | 140,548 | 0 | 0 | ||
| BIOCRYST PHARMACEUTICALS | COM | 09058V103 | 13,641 | 1,196,603 | SH | SOLE | 1,196,603 | 0 | 0 | ||
| BLUEBIRD BIO INC | COM | 09609G100 | 14,318 | 167,367 | SH | SOLE | 167,367 | 0 | 0 | ||
| BLUEPRINT MEDICINES CORP | COM | 09627Y109 | 18,744 | 878,348 | SH | SOLE | 878,348 | 0 | 0 | ||
| CIDARA THERAPEUTICS INC | COM | 171757107 | 15,017 | 1,180,570 | SH | SOLE | 1,180,570 | 0 | 0 | ||
| COHERUS BIOSCIENCES INC | COM | 19249H103 | 26,153 | 1,305,020 | SH | SOLE | 1,305,020 | 0 | 0 | ||
| COLLEGIUM PHARMACEUTICAL INC | COM | 19459J104 | 34,341 | 1,553,175 | SH | SOLE | 1,553,175 | 0 | 0 | ||
| DICERNA PHARMACEUTICALS INC | COM | 253031108 | 19,939 | 2,428,571 | SH | SOLE | 2,428,571 | 0 | 0 | ||
| DURECT CORP | COM | 266605104 | 745 | 381,800 | SH | SOLE | 381,800 | 0 | 0 | ||
| DYAX CORP | COM | 26746E103 | 48,702 | 2,551,193 | SH | SOLE | 2,551,193 | 0 | 0 | ||
| EPIZYME INC | COM | 29428V104 | 2,920 | 227,092 | SH | SOLE | 227,092 | 0 | 0 | ||
| GLOBAL BLOOD THERAPEUTICS INC | COM | 37890U108 | 19,273 | 457,142 | SH | SOLE | 457,142 | 0 | 0 | ||
| INTRA CELLULAR THERAPIES INC | COM | 46116X101 | 12,587 | 314,349 | SH | SOLE | 314,349 | 0 | 0 | ||
| NATERA INC | COM | 632307104 | 8,501 | 783,521 | SH | SOLE | 783,521 | 0 | 0 | ||
| NEURODERM LTD | ORD SHS | M74231107 | 8,785 | 425,000 | SH | SOLE | 425,000 | 0 | 0 | ||
| NIVALIS THERAPEUTICS INC | COM | 65481J109 | 7,949 | 612,863 | SH | SOLE | 612,863 | 0 | 0 | ||
| NOVAVAX INC | COM | 670002104 | 1,146 | 162,060 | SH | SOLE | 162,060 | 0 | 0 | ||
| PRONAI THERAPEUTICS INC | COM | 74346L101 | 12,414 | 604,982 | SH | SOLE | 604,982 | 0 | 0 | ||
| PROTEON THERAPEUTICS INC | COM | 74371L109 | 20,961 | 1,506,872 | SH | SOLE | 1,506,872 | 0 | 0 | ||
| REGULUS THERAPEUTICS INC | COM | 75915K101 | 26,420 | 4,039,823 | SH | SOLE | 4,039,823 | 0 | 0 | ||
| SANGAMO BIOSCIENCES INC | COM | 800677106 | 8,152 | 1,445,430 | SH | SOLE | 1,445,430 | 0 | 0 | ||
| SERES THERAPEUTICS INC | COM | 81750R102 | 7,311 | 246,645 | SH | SOLE | 246,645 | 0 | 0 | ||
| TENAX THERAPEUTICS INC | COM | 88032L100 | 8,011 | 2,670,300 | SH | SOLE | 2,670,300 | 0 | 0 | ||
| TG THERAPEUTICS INC | COM | 88322Q108 | 31,495 | 3,124,480 | SH | SOLE | 3,124,480 | 0 | 0 | ||
| THERAPEUTICSMD INC | COM | 88338N107 | 8,898 | 1,518,460 | SH | SOLE | 1,518,460 | 0 | 0 | ||
| ULTRAGENYX PHARMACEUTICAL INC | COM | 90400D108 | 5,400 | 56,067 | SH | SOLE | 56,067 | 0 | 0 | ||
| VICAL INC | COM | 925602104 | 958 | 2,084,078 | SH | SOLE | 2,084,078 | 0 | 0 | ||
| VITAE PHARMACEUTICALS INC | COM | 92847N103 | 3,536 | 321,161 | SH | SOLE | 321,161 | 0 | 0 | ||
| WAFERGEN BIO-SYSTEMS INC | COM PAR$ | 93041P308 | 279 | 205,400 | SH | SOLE | 205,400 | 0 | 0 | ||
| XENCOR INC | COM | 98401F105 | 8,315 | 679,885 | SH | SOLE | 679,885 | 0 | 0 | ||
| ZOGENIX INC | COM NEW | 98978L204 | 22,673 | 1,679,500 | SH | SOLE | 1,679,500 | 0 | 0 | ||
| ZYNERBA PHARMACEUTICALS INC | COM | 98986X109 | 7,513 | 525,000 | SH | SOLE | 525,000 | 0 | 0 | ||