The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AbbVie Inc. Common 00287Y109 11,708 200,000 SH Call SOLE   200,000 0 0
AbbVie Inc. Common 00287Y109 65,015 1,110,614 SH   SOLE   1,110,614 0 0
Accelerate Diagnostics, Inc Common 00430H102 3,254 144,625 SH   SOLE   144,625 0 0
Accuray, Inc. Common 004397105 6,807 731,943 SH   SOLE   731,943 0 0
Achillion Pharmaceuticals Inc. Common 00448Q201 5,396 547,300 SH   SOLE   547,300 0 0
Achillion Pharmaceuticals Inc. Common 00448Q201 5,396 547,300 SH Call SOLE   547,300 0 0
Acorda Therapeutics, Inc. Common 00484M106 22,659 680,862 SH   SOLE   680,862 0 0
Actavis plc Shares G0083B108 107,645 361,686 SH   SOLE   361,686 0 0
Actavis plc Preferred Convertible Series A G0083B116 5,060 5,000 SH   SOLE   5,000 0 0
Aegerion Pharmaceuticals, Inc. Common 00767E102 5,391 206,000 SH   SOLE   206,000 0 0
Aetna, Inc. Common 00817Y108 35,361 331,931 SH   SOLE   331,931 0 0
Agios Pharmaceuticals, Inc. Common 00847X104 9,458 100,300 SH   SOLE   100,300 0 0
Akorn, Inc. Common 009728106 40,359 849,482 SH   SOLE   849,482 0 0
Alere, Inc. Common 01449J105 14,567 297,901 SH   SOLE   297,901 0 0
Alexion Pharmaceuticals, Inc. Common 015351109 13,379 77,200 SH Call SOLE   77,200 0 0
Alexion Pharmaceuticals, Inc. Common 015351109 87,049 502,305 SH   SOLE   502,305 0 0
Alkermes plc Shares G01767105 35,879 588,470 SH   SOLE   588,470 0 0
Allscripts Healthcare Solutions, Inc. Common 01988P108 21,267 1,778,200 SH   SOLE   1,778,200 0 0
Alnylam Pharmaceuticals, Inc. Common 02043Q107 5,670 54,300 SH Call SOLE   54,300 0 0
Alnylam Pharmaceuticals, Inc. Common 02043Q107 13,595 130,195 SH   SOLE   130,195 0 0
Amgen, Inc. Common 031162100 56,232 351,779 SH   SOLE   351,779 0 0
Athenahealth, Inc. Common 04685W103 2,758 23,100 SH Call SOLE   23,100 0 0
Athenahealth, Inc. Common 04685W103 2,758 23,100 SH   SOLE   23,100 0 0
Baxter International, Inc. Common 071813109 21,893 319,600 SH   SOLE   319,600 0 0
Bellicum Pharmaceuticals, Inc. Common 079481107 1,390 60,000 SH   SOLE   60,000 0 0
BioDelivery Sciences International, Inc. Common 09060J106 2,625 250,000 SH   SOLE   250,000 0 0
Biogen Idec, Inc. Common 09062X103 5,151 12,200 SH Call SOLE   12,200 0 0
Biogen Idec, Inc. Common 09062X103 143,343 339,483 SH   SOLE   339,483 0 0
BioMarin Pharmaceutical Inc. Common 09061G101 66,669 534,977 SH   SOLE   534,977 0 0
bluebird bio, Inc. Common 09609G100 6,585 54,527 SH   SOLE   54,527 0 0
Bristol-Myers Squibb Co. Common 110122108 34,523 535,240 SH   SOLE   535,240 0 0
Catamaran Corporation Common 148887102 25,817 433,600 SH   SOLE   433,600 0 0
Celgene Corporation Common 151020104 229,964 1,994,834 SH   SOLE   1,994,834 0 0
Cellectis S.A. Sponsored ADS 15117K103 1,384 40,000 SH   SOLE   40,000 0 0
Centene Corporation Common 15135B101 8,483 120,000 SH   SOLE   120,000 0 0
Cigna Corp Common 125509109 9,611 74,251 SH   SOLE   74,251 0 0
Community Health Systems, Inc. Common 203668108 2,614 50,000 SH Call SOLE   50,000 0 0
Community Health Systems, Inc. Common 203668108 10,956 209,572 SH   SOLE   209,572 0 0
Corsicanto Ltd. Note 3.5% 1/15/32 220480AB3 15,656 14,700,000 PRN   SOLE   14,700,000 0 0
Eleven Biotherapeutics, Inc. Common 286221106 1,748 195,964 SH   SOLE   195,964 0 0
Endo International PLC Shares G30401106 22,584 251,773 SH   SOLE   251,773 0 0
Endologix Inc. Common 29266S106 9,406 551,000 SH   SOLE   551,000 0 0
Epizyme, Inc. Common 29428V104 3,756 200,000 SH   SOLE   200,000 0 0
Flex Pharma, Inc. Common 33938A105 4,559 232,600 SH   SOLE   232,600 0 0
Gilead Sciences, Inc. Common 375558103 42,206 430,100 SH Call SOLE   430,100 0 0
Gilead Sciences, Inc. Common 375558103 223,710 2,279,731 SH   SOLE   2,279,731 0 0
HCA Holdings, Inc. Common 40412C101 11,096 147,488 SH   SOLE   147,488 0 0
Health Care REIT Inc. Common 42217K601 13,432 200,000 SH   SOLE   200,000 0 0
Heron Therapeutics, Inc. Common 427746102 12,716 873,940 SH   SOLE   873,940 0 0
IDEXX Laboratories, Inc. Common 45168D104 8,692 56,265 SH   SOLE   56,265 0 0
Illumina, Inc. Common 452327109 5,458 29,400 SH Call SOLE   29,400 0 0
Illumina, Inc. Common 452327109 24,735 133,241 SH   SOLE   133,241 0 0
Immunomedics, Inc. Common 452907108 1,915 500,000 SH   SOLE   500,000 0 0
Impax Laboratories, Inc. Common 45256B101 16,155 344,683 SH   SOLE   344,683 0 0
Incyte Corporation Common 45337C102 5,133 56,000 SH Call SOLE   56,000 0 0
Incyte Corporation Common 45337C102 85,836 936,461 SH   SOLE   936,461 0 0
Infinity Pharmaceuticals, Inc. Common 45665G303 6,132 438,623 SH   SOLE   438,623 0 0
IntelliPharmaCeutics International Inc. Common 458173101 3,889 1,394,000 SH   SOLE   1,394,000 0 0
Intra-Cellular Therapies, Inc. Common 46116X101 3,582 150,000 SH   SOLE   150,000 0 0
Ironwood Pharmaceuticals, Inc. Common 46333X108 12,289 768,050 SH   SOLE   768,050 0 0
Ishares Nasdaq Biotechnology ETF ETF 464287556 19,806 57,670 SH   SOLE   57,670 0 0
Jazz Pharmaceuticals plc Shares G50871105 20,863 120,741 SH   SOLE   120,741 0 0
Johnson & Johnson Common 478160104 43,722 434,612 SH   SOLE   434,612 0 0
Karyopharm Therapeutics Inc. Common 48576U106 14,600 476,966 SH   SOLE   476,966 0 0
Kite Pharma, Inc. Common 49803L109 2,682 46,500 SH Call SOLE   46,500 0 0
Kite Pharma, Inc. Common 49803L109 2,682 46,500 SH   SOLE   46,500 0 0
KYTHERA Biopharmaceuticals Inc Common 501570105 2,794 55,717 SH   SOLE   55,717 0 0
LTC Properties Inc. Common 502175102 10,884 236,618 SH   SOLE   236,618 0 0
Macrogenics, Inc. Common 556099109 400 12,743 SH   SOLE   12,743 0 0
McKesson Corporation Common 58155Q103 15,350 67,862 SH   SOLE   67,862 0 0
Medical Properties Trust Inc. Common 58463J304 17,004 1,153,574 SH   SOLE   1,153,574 0 0
Merck & Co., Inc. Common 58933Y105 10,634 185,000 SH   SOLE   185,000 0 0
Merrimack Pharmaceuticals, Inc. Note 4.50% 7/15/20 590328AA8 2,929 1,485,000 PRN   SOLE   1,485,000 0 0
Merrimack Pharmaceuticals, Inc. Common 590328100 6,745 567,787 SH   SOLE   567,787 0 0
Molina Healthcare, Inc. Common 60855R100 23,410 347,901 SH   SOLE   347,901 0 0
Momenta Pharmaceuticals, Inc. Common 60877T100 5,374 353,575 SH   SOLE   353,575 0 0
Mylan NV Shares Euro N59465109 59,950 1,010,105 SH   SOLE   1,010,105 0 0
Myriad Genetics, Inc. Shares Euro 62855J104 2,648 74,800 SH Call SOLE   74,800 0 0
Myriad Genetics, Inc. Common 62855J104 2,648 74,800 SH   SOLE   74,800 0 0
Neurocrine Biosciences, Inc. Common 64125C109 19,901 501,150 SH   SOLE   501,150 0 0
Omega Healthcare Investors Inc. Common 681936100 16,760 413,116 SH   SOLE   413,116 0 0
OncoGenex Pharmaceuticals, Inc. Common 68230A106 243 113,100 SH   SOLE   113,100 0 0
Perrigo Company plc Common G97822103 11,208 67,700 SH Call SOLE   67,700 0 0
Perrigo Company plc Shares G97822103 21,629 130,652 SH   SOLE   130,652 0 0
Pfizer, Inc. Common 717081103 56,994 1,638,241 SH   SOLE   1,638,241 0 0
Physicians Realty Trust Common 71943U104 18,506 1,050,902 SH   SOLE   1,050,902 0 0
Receptos, Inc. Common 756207106 20,578 124,800 SH   SOLE   124,800 0 0
Regeneron Pharmaceuticals, Inc. Common 75886F107 84,502 187,166 SH   SOLE   187,166 0 0
Sabra Health Care REIT Inc. Common 78573L106 15,123 456,190 SH   SOLE   456,190 0 0
Sage Therapeutics, Inc. Common 78667J108 753 15,000 SH   SOLE   15,000 0 0
Sagent Pharmaceuticals, Inc. Common 786692103 9,521 409,500 SH   SOLE   409,500 0 0
Sangamo BioSciences, Inc. Common 800677106 10,648 679,100 SH   SOLE   679,100 0 0
Sarepta Therapeutics, Inc. Common 803607100 1,529 115,100 SH Call SOLE   115,100 0 0
Sarepta Therapeutics, Inc. Common 803607100 3,058 230,300 SH   SOLE   230,300 0 0
Senior Housing Properties Trust Shares 81721M109 10,642 479,604 SH   SOLE   479,604 0 0
Sorrento Therapeutics, Inc. Common 83587F202 1,648 142,597 SH   SOLE   142,597 0 0
Spectrum Pharmaceuticals, Inc. Note 2.75% 12/15/18 84763AAB4 4,572 5,000,000 PRN   SOLE   5,000,000 0 0
St Jude Medical, Inc. Common 790849103 10,563 161,510 SH   SOLE   161,510 0 0
Stryker Corporation Common 863667101 11,433 123,940 SH   SOLE   123,940 0 0
Supernus Pharmaceuticals, Inc. Note 7.50% 5/1/19 868459AB4 4,826 2,000,000 PRN   SOLE   2,000,000 0 0
Synageva BioPharma Corp Common 87159A103 6,925 71,000 SH Call SOLE   71,000 0 0
Synageva BioPharma Corp Common 87159A103 19,378 198,689 SH   SOLE   198,689 0 0
Tenet Healthcare Corp Common 88033G407 2,946 59,500 SH   SOLE   59,500 0 0
Teva Pharmaceutical Industries Ltd. ADR 881624209 62,150 997,594 SH   SOLE   997,594 0 0
TherapeuticsMD, Inc. Common 88338N107 8,963 1,481,500 SH   SOLE   1,481,500 0 0
Thermo Fisher Scientific Inc. Common 883556102 19,035 141,695 SH   SOLE   141,695 0 0
TrovaGene, Inc. Common 897238309 4,427 650,000 SH   SOLE   650,000 0 0
Ventas Inc. Common 92276F100 21,379 292,782 SH   SOLE   292,782 0 0
Verastem, Inc. Common 92337C104 12,711 1,249,827 SH   SOLE   1,249,827 0 0
Vertex Pharmaceuticals, Inc. Common 92532F100 54,767 464,244 SH   SOLE   464,244 0 0
WellCare Health Plans Inc. Common 94946T106 8,108 88,652 SH   SOLE   88,652 0 0
Wright Medical Group Inc. Common 98235T107 4,027 156,100 SH   SOLE   156,100 0 0
Xencor, Inc. Common 98401F105 306 20,000 SH   SOLE   20,000 0 0
Zafgen, Inc. Common 98885E103 527 13,307 SH   SOLE   13,307 0 0
Zimmer Holdings, Inc. Common 98956P102 12,022 102,300 SH   SOLE   102,300 0 0
Zogenix, Inc. Common 98978L105 3,906 2,850,811 SH   SOLE   2,850,811 0 0