The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COM 003654100 55,496 2,207,489 SH   SOLE 2,207,489 0 0
ALIGN TECHNOLOGY INC COM 016255101 9,907 176,788 SH   SOLE 176,788 0 0
ALIMERA SCIENCES INC COM 016259103 21,737 3,634,984 SH   SOLE 3,634,984 0 0
ALLERGAN INC COM 018490102 12,505 73,900 SH   SOLE 73,900 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 33,453 1,614,536 SH   SOLE 1,614,536 0 0
AMICUS THERAPEUTICS INC COM 03152W109 13,265 3,971,576 SH   SOLE 3,971,576 0 0
ANACOR PHARMACEUTICALS INC COM 032420101 29,460 1,661,612 SH   SOLE 1,661,612 0 0
ARIAD PHARMACEUTICALS INC COM 04033A100 14,496 2,275,603 SH   SOLE 2,275,603 0 0
AUXILIUM PHARMACEUTICALS INC COM 05334D107 97,384 4,854,631 SH   SOLE 4,854,631 0 0
AVEO PHARMACEUTICALS INC COM 053588109 2,197 1,200,800 SH   SOLE 1,200,800 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 56,959 915,587 SH   SOLE 915,587 0 0
BIOSPECIFICS TECHNOLOGIES CO COM 090931106 302 11,184 SH   SOLE 11,184 0 0
CELGENE CORP COM 151020104 13,327 155,180 SH   SOLE 155,180 0 0
CELLADON CORP COM 15117E107 23,522 1,468,300 SH   SOLE 1,468,300 0 0
CLOVIS ONCOLOGY INC COM 189464100 37,903 915,321 SH   SOLE 915,321 0 0
CUBIST PHARMACEUTICALS INC COM 229678107 106,609 1,526,916 SH   SOLE 1,526,916 0 0
CYBERONICS INC COM 23251P102 107,146 1,715,430 SH   SOLE 1,715,430 0 0
CYTOKINETICS INC COM NEW 23282W605 591 123,686 SH   SOLE 123,686 0 0
EXACT SCIENCES CORP COM 30063P105 13,244 777,676 SH   SOLE 777,676 0 0
GERON CORP COM 374163103 4,043 1,259,500 SH   SOLE 1,259,500 0 0
GILEAD SCIENCES INC COM 375558103 12,801 154,400 SH   SOLE 154,400 0 0
HYPERION THERAPEUTICS INC COM 44915N101 1,636 62,700 SH   SOLE 62,700 0 0
INSMED INC COM PAR $.01 457669307 19,223 962,101 SH   SOLE 962,101 0 0
INTERMUNE INC COM 45884X103 226,669 5,134,058 SH   SOLE 5,134,058 0 0
INTUITIVE SURGICAL INC COM NEW 46120e602 7,577 18,400 SH   SOLE 18,400 0 0
KYTHERA BIOPHARMACEUTICALS I COM 501570105 36,450 949,959 SH   SOLE 949,959 0 0
MEDIVATION INC COM 58501N101 9,473 122,900 SH   SOLE 122,900 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 17,579 1,455,176 SH   SOLE 1,455,176 0 0
NPS PHARMACEUTICALS INC COM 62936P103 20,137 609,300 SH   SOLE 609,300 0 0
OREXIGEN THERAPEUTICS INC COM 686164104 11,936 1,931,324 SH   SOLE 1,931,324 0 0
PROTHENA CORP PLC SHS G72800108 12,042 534,018 SH   SOLE 534,018 0 0
QLT INC COM 746927102 11,663 1,887,208 SH   SOLE 1,887,208 0 0
QUESTCOR PHARMACEUTICALS INC COM 74835Y101 20,255 218,995 SH   SOLE 218,995 0 0
REVANCE THERAPEUTICS INC COM 761330109 3,117 91,669 SH   SOLE 91,669 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 18,804 5,180,101 SH   SOLE 5,180,101 0 0
SEQUENOM INC COM NEW 817337405 37,966 9,810,442 SH   SOLE 9,810,442 0 0
SHIRE PLC SPONSORED ADR 82481R106 15,001 63,700 SH   SOLE 63,700 0 0
SOPHIRIS BIO INC COM NEW 83578Q209 656 292,900 SH   SOLE 292,900 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 43,672 2,599,553 SH   SOLE 2,599,553 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 107,412 1,213,828 SH   SOLE 1,213,828 0 0
VANDA PHARMACEUTICALS INC COM 921659108 52,430 3,240,424 SH   SOLE 3,240,424 0 0
XOMA CORP DEL COM 98419J107 2,868 624,900 SH   SOLE 624,900 0 0