The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COM 003654100 93,632 2,460,124 SH   SOLE 2,460,124 0 0
ACELRX PHARMACEUTICALS INC COM 00444T100 14,325 2,128,539 SH   SOLE 2,128,539 0 0
ALIGN TECHNOLOGY INC COM 016255101 13,100 234,300 SH   SOLE 234,300 0 0
ALIMERA SCIENCES INC COM 016259103 16,696 3,013,793 SH   SOLE 3,013,793 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 84,993 1,994,200 SH   SOLE 1,994,200 0 0
AMICUS THERAPEUTICS INC COM 03152W109 16,277 1,956,376 SH   SOLE 1,956,376 0 0
ANACOR PHARMACEUTICALS INC COM 032420101 81,329 2,521,822 SH   SOLE 2,521,822 0 0
ARIAD PHARMACEUTICALS INC COM 04033A100 15,332 2,231,717 SH   SOLE 2,231,717 0 0
AUXILIUM PHARMACEUTICALS INC COM 05334D107 169,034 4,915,931 SH   SOLE 4,915,931 0 0
AVEO PHARMACEUTICALS INC COM 053588109 562 669,449 SH   SOLE 669,449 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 117,719 1,302,197 SH   SOLE 1,302,197 0 0
BIOSPECIFICS TECHNOLOGIES CO COM 090931106 1,948 50,436 SH   SOLE 50,436 0 0
CELGENE CORP COM 151020104 24,106 215,500 SH   SOLE 215,500 0 0
CELLADON CORP COM 15117E107 27,416 1,403,800 SH   SOLE 1,403,800 0 0
CLOVIS ONCOLOGY INC COM 189464100 117,760 2,102,857 SH   SOLE 2,102,857 0 0
CUBIST PHARMACEUTICALS INC COM 229678107 131,214 1,303,668 SH   SOLE 1,303,668 0 0
CYBERONICS INC COM 23251P102 89,539 1,608,101 SH   SOLE 1,608,101 0 0
CYTOKINETICS INC COM NEW 23282W605 991 123,686 SH   SOLE 123,686 0 0
EXACT SCIENCES CORP COM 30063P105 10,737 391,276 SH   SOLE 391,276 0 0
GILEAD SCIENCES INC COM 375558103 22,113 234,600 SH   SOLE 234,600 0 0
HISTOGENICS CORP COM 43358V109 5,000 454,545 SH   SOLE 454,545 0 0
HYPERION THERAPEUTICS INC COM 44915N101 1,505 62,700 SH   SOLE 62,700 0 0
INSMED INC COM PAR $.01 457669307 71,559 4,625,648 SH   SOLE 4,625,648 0 0
INTREXON CORP COM 46122T102 1,203 43,700 SH   SOLE 43,700 0 0
INTUITIVE SURGICAL INC COM NEW 46120e602 13,779 26,050 SH   SOLE 26,050 0 0
KYTHERA BIOPHARMACEUTICALS I COM 501570105 38,907 1,121,884 SH   SOLE 1,121,884 0 0
MALLINCKRODT PUB LTD CO SHS G5785G107 355 3,588 SH   SOLE 3,588 0 0
MEDIVATION INC COM 58501N101 16,067 161,300 SH   SOLE 161,300 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 17,520 1,455,176 SH   SOLE 1,455,176 0 0
NPS PHARMACEUTICALS INC COM 62936P103 42,576 1,190,263 SH   SOLE 1,190,263 0 0
NXSTAGE MEDICAL INC COM 67072V103 362 20,200 SH   SOLE 20,200 0 0
OREXIGEN THERAPEUTICS INC COM 686164104 11,704 1,931,324 SH   SOLE 1,931,324 0 0
PROTHENA CORP PLC SHS G72800108 14,350 691,218 SH   SOLE 691,218 0 0
QLT INC COM 746927102 6,950 1,733,208 SH   SOLE 1,733,208 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 11,750 5,176,319 SH   SOLE 5,176,319 0 0
SALIX PHARMACEUTICALS INC COM 795435106 8,816 76,700 SH   SOLE 76,700 0 0
SEQUENOM INC COM NEW 817337405 36,725 9,925,742 SH   SOLE 9,925,742 0 0
SHIRE PLC SPONSORED ADR 82481R106 18,193 85,600 SH   SOLE 85,600 0 0
SOPHIRIS BIO INC COM NEW 83578Q209 103 191,600 SH   SOLE 191,600 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 23,956 2,629,622 SH   SOLE 2,629,622 0 0
THORATEC CORP COM NEW 885175307 8,727 268,861 SH   SOLE 268,861 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 181,691 1,403,128 SH   SOLE 1,403,128 0 0
VANDA PHARMACEUTICALS INC COM 921659108 54,229 3,786,908 SH   SOLE 3,786,908 0 0
WRIGHT MED GROUP INC COM 98235T107 54,808 2,039,751 SH   SOLE 2,039,751 0 0
XOMA CORP DEL COM 98419J107 2,852 794,500 SH   SOLE 794,500 0 0
ZELTIQ AESTHETICS INC COM 98933Q108 11,010 394,486 SH   SOLE 394,486 0 0