The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACHILLION PHARMACEUTICALS COM 00448Q201 2,382 241,600 SH   SOLE 241,600 0 0
ACTINIUM PHARMACEUTICALS INC COM 00507W107 222 90,000 SH   SOLE 90,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 5,022 160,242 SH   SOLE 160,242 0 0
AFFIMED THERAPEUTICS BV COM N01045108 394 62,500 SH   SOLE 62,500 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 356 35,000 SH   SOLE 35,000 0 0
APPLIED GENETIC TECHNOL CORP COM 03820J100 2,185 109,323 SH   SOLE 109,323 0 0
APTOSE BIOSCIENCES INC COM NEW 03835T200 121 22,289 SH   SOLE 22,289 0 0
ASCENDIS PHARMA A S SPONSORED ADR ADDED 04351P101 1,623 93,541 SH   SOLE 93,541 0 0
ATRICURE INC COM 04963C209 13,061 637,431 SH   SOLE 637,431 0 0
AUSPEX PHARMACEUTICALS INC COM 05211J102 12,083 120,500 SH   SOLE 120,500 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 1,505 166,656 SH   SOLE 166,656 0 0
BIOTELEMETRY INC COM 090672106 2,085 235,645 SH   SOLE 235,645 0 0
BLUEBIRD BIO INC COM 09609G100 966 8,000 SH   SOLE 8,000 0 0
BOVIE MEDICAL CORP COM 10211F100 239 100,000 SH   SOLE 100,000 0 0
CARDICA INC COM 14141R101 936 1,486,004 SH   SOLE 1,486,004 0 0
CAREDX INC COM 14167L103 687 123,883 SH   SOLE 123,883 0 0
CAS MEDICAL SYSTEMS INC COM PAR $0.004 124769209 134 100,000 SH   SOLE 100,000 0 0
CHECK CAP LTD SHS ADDED M2361E112 605 110,000 SH   SOLE 110,000 0 0
CHECK CAP LTD-CW20 *W EXP 02/28/202 ADDED M2361E120 55 55,000 SH   SOLE 55,000 0 0
CHEMBIO DIAGNOSTICS INC COM NEW 163572209 106 26,287 SH   SOLE 26,287 0 0
CLOVIS ONCOLOGY INC COM 189464100 1,737 23,400 SH   SOLE 23,400 0 0
COGENTIX MEDICAL INC COM 19243A104 593 353,181 SH   SOLE 353,181 0 0
CURIS INC COM 231269101 720 299,800 SH   SOLE 299,800 0 0
CUTERA INC COM 232109108 303 23,490 SH   SOLE 23,490 0 0
CYNAPSUS THERAPEUTICS INC COM 23257Y156 521 543,927 SH   SOLE 543,927 0 0
CYNAPSUS THERAPEUTICS INC COM 23257Y701 687 717,200 SH   SOLE 717,200 0 0
CYTRX CORP COM PAR $.001 232828509 1,014 300,813 SH   SOLE 300,813 0 0
DERMA SCIENCES INC COM PAR $.01 249827502 3,167 373,918 SH   SOLE 373,918 0 0
DISCOVERY LABORATORIES INC COM NEW 254668403 5,748 4,829,874 SH   SOLE 4,829,874 0 0
ENCISION INC COM 29254Q104 829 1,062,500 SH   SOLE 1,062,500 0 0
EPIZYME INC COM 29428V104 376 20,000 SH   SOLE 20,000 0 0
ESSA PHARMA INC COM 29668H104 1,422 250,000 SH   SOLE 250,000 0 0
EXACTECH INC COM 30064E109 811 31,636 SH   SOLE 31,636 0 0
FATE THERAPEUTICS INC COM 31189P102 99 20,190 SH   SOLE 20,190 0 0
GALENA BIOPHARMA INC COM 363256108 348 250,000 SH   SOLE 250,000 0 0
GENVEC INC COM NEW 37246C307 295 100,000 SH   SOLE 100,000 0 0
GLOBEIMMUNE INC COM 37957B100 69 9,445 SH   SOLE 9,445 0 0
INSULET CORP COM 45784P101 3,536 106,018 SH   SOLE 106,018 0 0
INSULET CORP NOTE 2.000% 6/1 45784PAD3 2,419 2,407,000 PRN   SOLE 2,407,000 0 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108 564 2,000 SH   SOLE 2,000 0 0
JOHNSON AND JOHNSON COM 478160104 946 9,400 SH   SOLE 9,400 0 0
KERYX BIOPHARMACEUTICALS COM 492515101 443 34,800 SH   SOLE 34,800 0 0
LPATH INC COM NEW 548910306 276 111,884 SH   SOLE 111,884 0 0
LUMENIS LTD SHS CL B M6778Q121 372 31,072 SH   SOLE 31,072 0 0
MASIMO CORPORATION COM 574795100 2,177 66,000 SH   SOLE 66,000 0 0
MINERVA NEUROSCIENCES INC COM 603380106 507 101,317 SH   SOLE 101,317 0 0
NANOSPHERE INC COM 63009F105 139 600,000 SH   SOLE 600,000 0 0
NEOTHETICS INC COM 64066G101 1,534 186,807 SH   SOLE 186,807 0 0
NOVADAQ TECHNOLOGIES INC COM 66987G102 1,654 101,841 SH   SOLE 101,841 0 0
NUVASIVE INC NOTE 2.750% 7/0 670704AC9 935 760,000 PRN   SOLE 760,000 0 0
NXSTAGE MEDICAL INC COM 67072V103 6,341 366,554 SH   SOLE 366,554 0 0
OPEXA THERAPEUTICS INC COM NEW 68372T202 0 500 SH   SOLE 500 0 0
OTONOMY INC COM 68906L105 1,768 50,000 SH   SOLE 50,000 0 0
PHARMACYCLICS INC COM 716933106 18,333 71,628 SH   SOLE 71,628 0 0
PROTALIX BIOTHERAPEUTICS INC COM 74365A101 2,191 1,230,789 SH   SOLE 1,230,789 0 0
PROTALIX BIOTHERAPEUTICS INC NOTE 4.500% 9/1 74365AAB7 3,060 4,000,000 PRN   SOLE 4,000,000 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 3,962 1,109,740 SH   SOLE 1,109,740 0 0
RTI SURGICAL INC COM 74975N105 424 85,918 SH   SOLE 85,918 0 0
SPECTRANETICS CORP COM 84760C107 1,384 39,812 SH   SOLE 39,812 0 0
STEREOTAXIS INC COM NEW 85916J409 2,815 1,372,862 SH   SOLE 1,372,862 0 0
SYNERON MEDICAL LTD ORD SHS M87245102 1,126 90,947 SH   SOLE 90,947 0 0
TANDEM DIABETES CARE INC COM 875372104 963 76,340 SH   SOLE 76,340 0 0
TARGACEPT INC COM 87611R306 1,382 465,293 SH   SOLE 465,293 0 0
THRESHOLD PHARMACEUTICALS COM NEW 885807206 2,540 625,558 SH   SOLE 625,558 0 0
TONIX PHARMACEUTICALS HLDG C COM NEW 890260201 91 14,400 SH   SOLE 14,400 0 0
TRANSITION THERAPEUTICS INC COM NEW 893716209 180 26,410 SH   SOLE 26,410 0 0
UNIQURE B.V. NV SHS N90064101 730 30,000 SH   SOLE 30,000 0 0
VENAXIS INC COM 92262A107 305 658,000 SH   SOLE 658,000 0 0
XENOPORT INC COM 98411C100 828 116,259 SH   SOLE 116,259 0 0
ZOGENIX INC COM 98978L105 1,170 853,700 SH   SOLE 853,700 0 0
ZS PHARMA INC COM 98979G105 1,645 39,100 SH   SOLE 39,100 0 0