The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AAC HLDGS INC COM 000307108 13,200 303,027 SH   DFND 1 303,027 0 0
ACCURAY INC NOTE 3.750% 8/0 004397AB1 24,565 24,100,000 PRN   DFND 1 24,100,000 0 0
ADEPTUS HEALTH INC CL A 006855100 34,576 364,000 SH   DFND 1 364,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 39,036 2,211,644 SH   DFND 1 2,211,644 0 0
AETNA INC NEW COM 00817Y108 47,127 369,739 SH   DFND 1 369,739 0 0
AKORN INC COM 009728106 15,048 344,667 SH   DFND 1 344,667 0 0
ALCOBRA LTD SHS M2239P109 7,118 1,088,449 SH   DFND 1 1,088,449 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 5,359 690,538 SH   DFND 1 690,538 0 0
ALIMERA SCIENCES INC COM 016259103 20,379 4,420,580 SH   DFND 1 4,420,580 0 0
ALLIQUA BIOMEDICAL INC COM NEW 019621200 8,849 1,679,111 SH   DFND 1 1,679,111 0 0
ALLSCRIPTS HEALTHCARE SOLUTN NOTE 1.250% 7/0 01988PAD0 103,524 100,750,000 PRN   DFND 1 100,750,000 0 0
ALPHATEC HOLDINGS INC COM 02081G102 6,876 4,982,738 SH   DFND 1 4,982,738 0 0
AMPHASTAR PHARMACEUTICALS IN COM 03209R103 7,885 448,532 SH   DFND 1 448,532 0 0
ANTARES PHARMA INC COM 036642106 38,251 18,389,789 SH   DFND 1 18,389,789 0 0
ANTHEM INC COM 036752103 23,112 140,806 SH   DFND 1 140,806 0 0
ARENA PHARMACEUTICALS INC COM 040047102 32,404 6,983,710 SH   DFND 1 6,983,710 0 0
ARRAY BIOPHARMA INC COM 04269X105 68,707 9,529,361 SH   DFND 1 9,529,361 0 0
ARRAY BIOPHARMA INC NOTE 3.000% 6/0 04269XAA3 56,942 45,000,000 PRN   DFND 1 45,000,000 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 369 20,859 SH   DFND 1 20,859 0 0
ATYR PHARMA INC COM 002120103 8,548 461,530 SH   DFND 1 461,530 0 0
AXOGEN INC COM 05463X106 11,701 3,726,439 SH   DFND 1 3,726,439 0 0
BIOTELEMETRY INC COM 090672106 6,076 644,300 SH   DFND 1 644,300 0 0
BIOTIE THERAPIES OYJ SPONSORED ADR 09074D103 4,385 219,558 SH   DFND 1 219,558 0 0
BLUEBIRD BIO INC COM 09609G100 55,020 326,783 SH   DFND 1 326,783 0 0
BOSTON SCIENTIFIC CORP COM 101137107 24,875 1,405,348 SH   DFND 1 1,405,348 0 0
BOVIE MEDICAL CORP COM 10211F100 1,920 688,229 SH   DFND 1 688,229 0 0
CAREDX INC COM 14167L103 1,489 229,000 SH   DFND 1 229,000 0 0
CAS MED SYS INC COM PAR $0.004 124769209 4,096 3,200,000 SH   DFND 1 3,200,000 0 0
CATABASIS PHARMACEUTICALS IN COM 14875P107 9,012 738,055 SH   DFND 1 738,055 0 0
CHARLES RIV LABS INTL INC COM 159864107 43,008 611,436 SH   DFND 1 611,436 0 0
CIDARA THERAPEUTICS INC COM 171757107 3,331 237,583 SH   DFND 1 237,583 0 0
CORSICANTO LTD NOTE 3.500% 1/1 220480AB3 1,084 1,000,000 PRN   DFND 1 1,000,000 0 0
DAVITA HEALTHCARE PARTNERS I COM 23918K108 50,543 636,000 SH   DFND 1 636,000 0 0
DBV TECHNOLOGIES S A SPONSORED ADR 23306J101 4,773 160,259 SH   DFND 1 160,259 0 0
DERMA SCIENCES INC COM PAR $.01 249827502 6,937 968,881 SH   DFND 1 968,881 0 0
DERMIRA INC COM 24983L104 8,712 496,387 SH   DFND 1 496,387 0 0
DISCOVERY LABORATORIES INC N COM NEW 254668403 2,489 3,659,700 SH   DFND 1 3,659,700 0 0
DYAX CORP COM 26746E103 65,813 2,483,507 SH   DFND 1 2,483,507 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 30,174 211,850 SH   DFND 1 211,850 0 0
EHEALTH INC COM 28238P109 41,428 3,264,588 SH   DFND 1 3,264,588 0 0
ENDOCHOICE HLDGS INC COM 29272U103 29,393 1,797,709 SH   DFND 1 1,797,709 0 0
ENDOLOGIX INC COM 29266S106 37,581 2,449,897 SH   DFND 1 2,449,897 0 0
ENDOLOGIX INC NOTE 2.250%12/1 29266SAA4 39,784 40,941,000 PRN   DFND 1 40,941,000 0 0
ESPERION THERAPEUTICS INC NE COM 29664W105 1,709 20,900 SH   DFND 1 20,900 0 0
EXELIXIS INC COM 30161Q104 15,040 4,000,000 SH Put DFND 1 4,000,000 0 0
FLAMEL TECHNOLOGIES SA SPONSORED ADR 338488109 86,303 4,072,809 SH   DFND 1 4,072,809 0 0
FLUIDIGM CORP DEL NOTE 2.750% 2/0 34385PAA6 30,952 35,000,000 PRN   DFND 1 35,000,000 0 0
FOAMIX PHARMACEUTICALS LTD SHS M46135105 9,727 948,934 SH   DFND 1 948,934 0 0
GALAPAGOS NV SPON ADR 36315X101 33,094 642,608 SH   DFND 1 642,608 0 0
GENESIS HEALTHCARE INC CL A COM 37185X106 13,989 2,119,616 SH   DFND 1 2,119,616 0 0
GENOCEA BIOSCIENCES INC COM 372427104 7,747 564,257 SH   DFND 1 564,257 0 0
GENOMIC HEALTH INC COM 37244C101 32,876 1,183,000 SH   DFND 1 1,183,000 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 57,340 1,376,722 SH   DFND 1 1,376,722 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 44,462 361,953 SH   DFND 1 361,953 0 0
HEALTHWAYS INC COM 422245100 29,531 2,465,042 SH   DFND 1 2,465,042 0 0
HEALTHWAYS INC NOTE 1.500% 7/0 422245AB6 25,929 27,915,000 PRN   DFND 1 27,915,000 0 0
HEARTWARE INTL INC NOTE 3.500%12/1 422368AA8 33,215 31,264,000 PRN   DFND 1 31,264,000 0 0
HORIZON PHARMA PLC SHS G4617B105 425,908 12,259,875 SH   DFND 1 12,259,875 0 0
HUMANA INC COM 444859102 14,442 75,500 SH   DFND 1 75,500 0 0
IMMUNOMEDICS INC COM 452907108 10,174 2,505,872 SH   DFND 1 2,505,872 0 0
IMPRIVATA INC COM 45323J103 15,675 958,152 SH   DFND 1 958,152 0 0
INFINITY PHARMACEUTICALS INC COM 45665G303 26,993 2,465,129 SH   DFND 1 2,465,129 0 0
INOGEN INC COM 45780L104 26,839 601,772 SH   DFND 1 601,772 0 0
INSMED INC COM PAR $.01 457669307 21,772 891,546 SH   DFND 1 891,546 0 0
INTEGRA LIFESCIENCES HLDGS C COM NEW 457985208 4,006 59,468 SH   DFND 1 59,468 0 0
INVITAE CORP COM 46185L103 2,480 166,666 SH   DFND 1 166,666 0 0
INVUITY INC COM NEW 46187J205 3,086 218,523 SH   DFND 1 218,523 0 0
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108 768 63,700 SH   DFND 1 63,700 0 0
JUNO THERAPEUTICS INC COM 48205A109 9,767 183,149 SH   DFND 1 183,149 0 0
KEMPHARM INC COM 488445107 19,921 1,084,443 SH   DFND 1 1,084,443 0 0
KINDRED BIOSCIENCES INC COM 494577109 1,904 279,204 SH   DFND 1 279,204 0 0
KINDRED HEALTHCARE INC COM 494580103 1,423 70,114 SH   DFND 1 70,114 0 0
LOXO ONCOLOGY INC COM 548862101 26,146 1,450,151 SH   DFND 1 1,450,151 0 0
MAZOR ROBOTICS LTD SPONSORED ADS 57886P103 3,474 261,000 SH   DFND 1 261,000 0 0
MCKESSON CORP COM 58155Q103 30,574 136,000 SH   DFND 1 136,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 12,514 397,660 SH   DFND 1 397,660 0 0
MYLAN N V SHS EURO N59465109 59,106 871,000 SH   DFND 1 871,000 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 19,008 1,232,696 SH   DFND 1 1,232,696 0 0
NIVALIS THERAPEUTICS INC COM 65481J109 56,546 3,732,412 SH   DFND 1 3,732,412 0 0
NUVASIVE INC COM 670704105 21,334 450,272 SH   DFND 1 450,272 0 0
NXSTAGE MEDICAL INC COM 67072V103 82,468 5,773,050 SH   DFND 1 5,773,050 0 0
ORTHOFIX INTL N V COM N6748L102 15,159 457,699 SH   DFND 1 457,699 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 7,773 561,226 SH   DFND 1 561,226 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 8,559 1,485,861 SH   DFND 1 1,485,861 0 0
PACIRA PHARMACEUTICALS INC COM 695127100 14,993 212,000 SH   DFND 1 212,000 0 0
PALATIN TECHNOLOGIES INC COM PAR $ .01 696077403 1,780 2,000,000 SH   DFND 1 2,000,000 0 0
PERRIGO CO PLC SHS G97822103 647 3,500 SH   DFND 1 3,500 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 15,024 329,837 SH   DFND 1 329,837 0 0
POZEN INC COM 73941U102 460 44,583 SH   DFND 1 44,583 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109 3,491 209,398 SH   DFND 1 209,398 0 0
PROTEON THERAPEUTICS INC COM 74371L109 22,599 1,265,343 SH   DFND 1 1,265,343 0 0
PSIVIDA CORP COM 74440J101 388 102,823 SH   DFND 1 102,823 0 0
RECEPTOS INC COM 756207106 380 2,000 SH   DFND 1 2,000 0 0
RELYPSA INC COM 759531106 7,445 225,000 SH   DFND 1 225,000 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 7,697 2,397,855 SH   DFND 1 2,397,855 0 0
RITE AID CORP COM 767754104 15,782 1,890,000 SH   DFND 1 1,890,000 0 0
SAGE THERAPEUTICS INC COM 78667J108 22,265 305,000 SH   DFND 1 305,000 0 0
SCYNEXIS INC COM 811292101 6,090 692,781 SH   DFND 1 692,781 0 0
SPARK THERAPEUTICS INC COM 84652J103 38,042 631,192 SH   DFND 1 631,192 0 0
SPECTRANETICS CORP MTNF 2.625% 6/0 84760CAA5 37,991 36,901,000 PRN   DFND 1 36,901,000 0 0
ST JUDE MED INC COM 790849103 7,871 107,719 SH   DFND 1 107,719 0 0
STEADYMED LTD SHS M84920103 6,744 1,267,577 SH   DFND 1 1,267,577 0 0
STREAMLINE HEALTH SOLUTIONS COM 86323X106 5,104 1,822,759 SH   DFND 1 1,822,759 0 0
SYNERON MEDICAL LTD ORD SHS M87245102 20,963 1,973,945 SH   DFND 1 1,973,945 0 0
TEVA PHARMACEUTICAL INDS LTD ADR 881624209 38,179 646,000 SH   DFND 1 646,000 0 0
TONIX PHARMACEUTICALS HLDG C COM NEW 890260201 11,800 1,315,551 SH   DFND 1 1,315,551 0 0
TRACON PHARMACEUTICALS INC COM 89237H100 5,495 485,000 SH   DFND 1 485,000 0 0
TRANSENTERIX INC COM NEW 89366M201 884 294,669 SH   DFND 1 294,669 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 3,760 172,307 SH   DFND 1 172,307 0 0
TRINITY BIOTECH PLC SPON ADR NEW 896438306 4,741 262,492 SH   DFND 1 262,492 0 0
TRUPANION INC COM 898202106 14,133 1,715,211 SH   DFND 1 1,715,211 0 0
UNIVERSAL AMERN CORP NEW COM 91338E101 44,626 4,409,703 SH   DFND 1 4,409,703 0 0
VANDA PHARMACEUTICALS INC COM 921659108 60,711 4,784,157 SH   DFND 1 4,784,157 0 0
VERACYTE INC COM 92337F107 4,269 383,256 SH   DFND 1 383,256 0 0
WALGREENS BOOTS ALLIANCE INC COM 931427108 54,759 648,501 SH   DFND 1 648,501 0 0
WEBMD HEALTH CORP NOTE 1.500%12/0 94770VAK8 24,636 23,000,000 PRN   DFND 1 23,000,000 0 0
XENCOR INC COM 98401F105 31,000 1,411,000 SH   DFND 1 1,411,000 0 0
ZAFGEN INC COM 98885E103 34,894 1,007,614 SH   DFND 1 1,007,614 0 0
ZELTIQ AESTHETICS INC COM 98933Q108 29,955 1,016,453 SH   DFND 1 1,016,453 0 0
ZS PHARMA INC COM 98979G105 6,915 132,000 SH   DFND 1 132,000 0 0