The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COMMON 003654100 32,605 298,338 SH   SOLE   146,338 0 152,000
ACADIA HEALTHCARE COMMON 00404A109 26,626 480,605 SH   SOLE   242,305 0 238,300
ACADIA PHARMACEUTCLS COMMON 004225108 960 29,582 SH   SOLE   29,582 0 0
ACCELERON PHARMA COMMON 00434H108 17,748 522,294 SH   SOLE   229,094 0 293,200
ACCURAY INC COMMON 004397105 4,286 825,875 SH   SOLE   1,050 0 824,825
ADEPTUS HEALTH INC CL A 006855100 31,983 619,108 SH   SOLE   317,223 0 301,885
ADVAXIS INC COM NEW 007624208 3,510 433,859 SH   SOLE   130,300 0 303,559
AERIE PHARMACEUTIC COMMON 00771V108 1,556 88,400 SH   SOLE   88,400 0 0
AGIOS PHARMACEUTIC COMMON 00847X104 1,512 36,100 SH   SOLE   36,100 0 0
ALDER BIOPHARMACEU COMMON 014339105 13,115 525,221 SH   SOLE   273,621 0 251,600
ALEXION PHARM INC COMMON 015351109 29,347 251,348 SH   SOLE   183,748 0 67,600
ALIGN TECH INC COMMON 016255101 19,826 246,127 SH   SOLE   128,290 0 117,837
ALNYLAM PHARMACUETCL COMMON 02043Q107 555 10,000 SH   SOLE   10,000 0 0
AMICUS THERAPEUTICS COMMON 03152W109 26,147 4,788,738 SH   SOLE   2,753,613 0 2,035,125
AMSURG CORP COMMON 03232P405 7,475 96,400 SH   SOLE   0 0 96,400
AVEXIS INC COMMON 05366U100 976 25,672 SH   SOLE   25,672 0 0
BIOMARIN PHARMAC INC COMMON 09061G101 38,498 494,836 SH   SOLE   361,439 0 133,397
CELGENE CORP COMMON 151020104 41,100 416,704 SH   SOLE   291,604 0 125,100
CHINA BIOLOGIC PROD COMMON 16938C106 626 5,890 SH   SOLE   5,890 0 0
COLLEGIUM PHARMACEUT COMMON 19459J104 3,489 294,400 SH   SOLE   0 0 294,400
DEXCOM INC COMMON 252131107 31,293 394,466 SH   SOLE   189,502 0 204,964
DR REDDYS LABS LTD ADR 256135203 1,647 32,155 SH   SOLE   32,155 0 0
ELI LILLY & CO COMMON 532457108 41,730 529,908 SH   SOLE   375,108 0 154,800
ENTELLUS MED INC COMMON 29363K105 2,668 146,006 SH   SOLE   310 0 145,696
GILEAD SCIENCES INC COMMON 375558103 39,716 476,102 SH   SOLE   339,202 0 136,900
GLOBAL BLOOD THERA COMMON 37890U108 16,378 987,224 SH   SOLE   622,477 0 364,747
INCYTE CORPORATION COMMON 45337C102 19,872 248,459 SH   SOLE   165,559 0 82,900
INTEGRA LIFESCIENCE COMMON 457985208 4,831 60,560 SH   SOLE   60 0 60,500
INTELLIA THERAPEUT COMMON 45826J105 1,466 123,159 SH   SOLE   123,159 0 0
INTERCEPT PHARMACE COMMON 45845P108 7,798 54,651 SH   SOLE   9,825 0 44,826
INTERSECT ENT INC COMMON 46071F103 2,497 193,140 SH   SOLE   300 0 192,840
INTUITIVE SURGIC INC COMMON 46120E602 12,748 19,274 SH   SOLE   14,816 0 4,458
LANNETT CO INC COMMON 516012101 2,443 102,693 SH   SOLE   110 0 102,583
MEDTRONIC PLC SHS G5960L103 36,906 425,333 SH   SOLE   322,486 0 102,847
MERCK & CO INC COMMON 58933Y105 42,802 742,960 SH   SOLE   529,560 0 213,400
MOLINA HEALTHCARE COMMON 60855R100 7,630 152,900 SH   SOLE   0 0 152,900
MOMENTA PHARMACEUTIC COMMON 60877T100 6,200 574,040 SH   SOLE   840 0 573,200
MYLAN N V SHS EURO N59465109 17,649 408,170 SH   SOLE   288,197 0 119,973
NEUROCRINE BIOSCIENC COMMON 64125C109 46,005 1,012,206 SH   SOLE   532,106 0 480,100
NEURODERM LTD ORD SHS M74231107 1,706 104,971 SH   SOLE   104,971 0 0
NOVAVAX INC COMMON 670002104 6,632 912,305 SH   SOLE   377,605 0 534,700
NOVO-NORDISK AS ADR 670100205 11,626 216,175 SH   SOLE   216,175 0 0
NUVASIVE INC COMMON 670704105 9,931 166,300 SH   SOLE   0 0 166,300
NXSTAGE MEDICAL COMMON 67072V103 39,644 1,828,582 SH   SOLE   940,626 0 887,956
OPHTHOTECH CORP COMMON 683745103 7,491 146,800 SH   SOLE   46,400 0 100,400
PFIZER INC COMMON 717081103 41,982 1,192,330 SH   SOLE   865,530 0 326,800
PORTOLA PHARMACEUTIC COMMON 737010108 29,013 1,229,382 SH   SOLE   591,440 0 637,942
PROFOUND MEDICAL COMMON 74319B106 605 541,500 SH   SOLE   541,500 0 0
PRONAI THERAPEUTICS COMMON 74346L101 1,359 201,660 SH   SOLE   201,660 0 0
PROTHENA CORP PLC SHS G72800108 6,109 174,746 SH   SOLE   51,146 0 123,600
PTC THERAPEUTICS I COMMON 69366J200 4,556 648,976 SH   SOLE   430,076 0 218,900
REGENXBIO INC COMMON 75901B107 3,379 367,541 SH   SOLE   156,741 0 210,800
SAGE THERAPEUTICS COMMON 78667J108 1,574 52,250 SH   SOLE   52,250 0 0
SAGENT PHARMACEUTI COMMON 786692103 15,104 1,008,265 SH   SOLE   408,402 0 599,863
SERES THERAPEUTICS COMMON 81750R102 598 20,600 SH   SOLE   20,600 0 0
SHIRE PLC SP ADR 82481R106 27,322 148,424 SH   SOLE   148,424 0 0
SURGICAL CARE AFFI COMMON 86881L106 4,686 98,300 SH   SOLE   0 0 98,300
TEAM HEALTH HLDGS COMMON 87817A107 7,154 175,900 SH   SOLE   0 0 175,900
TELADOC INC COMMON 87918A105 23,457 1,464,221 SH   SOLE   735,443 0 728,778
TEVA PHARMACEUTICAL ADR 881624209 30,938 615,935 SH   SOLE   615,935 0 0
UNIQURE N.V. SHS N90064101 2,559 347,271 SH   SOLE   100,471 0 246,800
UNITEDHEALTH GRP INC COMMON 91324P102 20,487 145,095 SH   SOLE   104,895 0 40,200
VERTEX PHARMACEUTICL COMMON 92532F100 19,920 231,575 SH   SOLE   167,175 0 64,400
WRIGHT MED GROUP N V ORD SHS 0.03 PAR N96617118 6,374 366,975 SH   SOLE   475 0 366,500