The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
|
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
|
||||||||||||||||
| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Accelerate Diagnostics Inc | COM | 00430H102 | 2,309 | 107,467 | SH | SOLE | 0 | 0 | 0 | ||
| Achillion Pharmaceuticals Inc | COM | 00448Q201 | 21,460 | 1,988,914 | SH | SOLE | 0 | 0 | 0 | ||
| Agenus Inc | COM NEW | 00847G705 | 10,054 | 2,214,453 | SH | SOLE | 0 | 0 | 0 | ||
| Atara Biotherapeutics Inc. | COM | 046513107 | 11,460 | 433,923 | SH | SOLE | 0 | 0 | 0 | ||
| Berkshire Hathaway Inc | CL B NEW | 084670702 | 7 | 50 | SH | SOLE | 0 | 0 | 0 | ||
| Celldex Therapeutics Inc | NEW COM | 15117B103 | 9,992 | 637,238 | SH | SOLE | 0 | 0 | 0 | ||
| CytRx Corp | COM PAR $.001 | 232828509 | 1,247 | 470,576 | SH | SOLE | 0 | 0 | 0 | ||
| Dicerna Pharmaceuticals Inc | COM | 253031108 | 23,890 | 2,012,662 | SH | SOLE | 0 | 0 | 0 | ||
| Five Prime Therapeutics Inc | COM | 33830X104 | 10,675 | 257,236 | SH | SOLE | 0 | 0 | 0 | ||
| Kite Pharma Inc | COM | 49803L109 | 25,815 | 418,935 | SH | SOLE | 0 | 0 | 0 | ||
| Mirati Therapeutics Inc | COM | 60468T105 | 12,180 | 385,456 | SH | SOLE | 0 | 0 | 0 | ||
| NVRO 05/20/2016 PUT 50 | COM | 64157F103 | 37 | 142 | SH | Put | SOLE | 0 | 0 | 0 | |
| Omeros Corp | COM | 682143102 | 28,618 | 1,819,341 | SH | SOLE | 0 | 0 | 0 | ||
| USO 01/15/2016 CALL 25 | UNITS | 91232N108 | 7 | 13,850 | SH | Call | SOLE | 0 | 0 | 0 | |
| VIVO 01/15/2016 CALL 20 | COM | 589584101 | 110 | 1,252 | SH | Call | SOLE | 0 | 0 | 0 | |
| Alnylam Pharmaceuticals Inc | COM | 02043Q107 | 53,976 | 573,361 | SH | SOLE | 0 | 0 | 0 | ||
| BioCryst Pharmaceuticals Inc | COM | 09058V103 | 20,748 | 2,010,501 | SH | SOLE | 0 | 0 | 0 | ||
| Bristol-Myers Squibb Co | COM | 110122108 | 7,546 | 109,701 | SH | SOLE | 0 | 0 | 0 | ||
| Corium International Inc | COM | 21887L107 | 6,040 | 743,865 | SH | SOLE | 0 | 0 | 0 | ||
| Dyax Corp | COM | 26746E103 | 4,356 | 115,795 | SH | SOLE | 0 | 0 | 0 | ||
| Global Blood Therapeutics Inc | ORD | 37890U108 | 5,663 | 175,156 | SH | SOLE | 0 | 0 | 0 | ||
| Invuity Inc | COM NEW | 46187J205 | 1,789 | 202,808 | SH | SOLE | 0 | 0 | 0 | ||
| La Jolla Pharmaceutical Co | COM PAR $.0001 2 | 503459604 | 29,279 | 1,084,416 | SH | SOLE | 0 | 0 | 0 | ||
| Lipocine Inc | NEW COM | 53630X104 | 2,851 | 220,515 | SH | SOLE | 0 | 0 | 0 | ||
| Regenxbio Inc | COM | 75901B107 | 3,674 | 221,326 | SH | SOLE | 0 | 0 | 0 | ||
| Symmetry Surgical Inc | COM | 87159G100 | 8,093 | 879,623 | SH | SOLE | 0 | 0 | 0 | ||
| Adaptimmune Therapeutics-adr | SPONDS ADR | 00653A107 | 85 | 7,055 | SH | SOLE | 0 | 0 | 0 | ||
| Biopharmx Corp | COM | 09072X101 | 563 | 370,636 | SH | SOLE | 0 | 0 | 0 | ||
| Nivalis Therapeutics Inc | COM | 65481J109 | 232 | 30,000 | SH | SOLE | 0 | 0 | 0 | ||