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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108 17,762 673,063 SH   SOLE   673,063 0 0
COLUCID PHARMACEUTICALS INC COM 19716T101 18,951 3,056,563 SH   SOLE   3,056,563 0 0
CORVUS PHARMACEUTICALS INC COM 221015100 45,734 3,154,046 SH   SOLE   3,154,046 0 0
GLAUKOS CORP COM 377322102 1,705 101,106 SH   SOLE   101,106 0 0
HTG MOLECULAR DIAGNOSTICS INC COM 40434H104 3,674 1,280,185 SH   SOLE   1,280,185 0 0
INOGEN INC COM 45780L104 159,648 3,549,320 SH   SOLE   3,549,320 0 0
INVUITY INC COM 46187J205 6,759 936,193 SH   SOLE   936,193 0 0
NABRIVA THERAPEUTICS AG COM 62957M104 7,840 874,985 SH   SOLE   874,985 0 0
OPHTHOTECH CORP COM 683745103 207,566 4,910,487 SH   SOLE   4,910,487 0 0
PENUMBRA, INC. COM 70975L107 12,107 263,191 SH   SOLE   263,191 0 0
SPECTRANETICS CORP COM 84760C107 3,439 236,826 SH   SOLE   236,826 0 0
TOBIRA THERAPEUTICS INC COM 88883P101 18,662 2,281,405 SH   SOLE   2,281,405 0 0
TOKAI PHARMACEUTICALS INC COM 88907J107 2,642 470,946 SH   SOLE   470,946 0 0
VANGUARD INDEX FDS TOTAL STK MKT 922908769 297,385 2,837,100 SH   SOLE   2,837,100 0 0
VANGUARD INTL EQUITY INDEX F FTSE EUROPE ETF 922042874 101,941 2,101,000 SH   SOLE   2,101,000 0 0
WRIGHT MED GROUP N V RIGHT 03/01/2019 N96617126 5,778 4,622,032 PRN   SOLE   0 0 4,622,032
XENON PHARMACEUTICALS INC COM 98420N105 892 127,563 SH   SOLE   127,563 0 0