SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
Meeker David P

(Last) (First) (Middle)
500 KENDALL STREET

(Street)
CAMBRIDGE MA 02142

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
GENZYME CORP [ GENZ ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director 10% Owner
X Officer (give title below) Other (specify below)
ExecVP,Chief Operating Officer
3. Date of Earliest Transaction (Month/Day/Year)
04/04/2011
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Genzyme common stock (GENZ) 04/04/2011 M 15,000 A $0(1) 25,551 D
Genzyme common stock (GENZ) 04/04/2011 M 14,250 A $0(1) 39,801 D
Genzyme common stock (GENZ) 04/04/2011 U 10,551 D $74 29,250 D
Genzyme common stock (GENZ) 04/04/2011 D 29,250 D $74 0.0000 D
Genzyme common stock (GENZ) 04/04/2011 U 210 D $74 0.0000 I By 401(k)
Genzyme common stock (GENZ) 04/04/2011 U 375 D $74 0.0000 I By Daughter
Genzyme common stock (GENZ) 04/04/2011 U 120 D $74 0.0000 I By Daughters
Genzyme common stock (GENZ) 04/04/2011 U 621 D $74 0.0000 I By Spouse
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Restricted Stock Units (1) 04/04/2011 M 14,250 05/21/2012(1) (1) Genzyme common stock (GENZ) 14,250 $0.0000 0.0000 D
Restricted Stock Units (1) 04/04/2011 M 15,000 05/22/2011(1) (1) Genzyme common stock (GENZ) 15,000 $0.0000 0.0000 D
Stock Option (right to buy) $51.52 04/04/2011 D 60,000 (2) 06/16/2020 Genzyme common stock (GENZ) 60,000 $51.52 0.0000 D
Stock Option (right to buy) $30.57 04/04/2011 D 15,000 03/06/2003(2) 03/06/2013 Genzyme common stock (GENZ) 15,000 $30.57 0.0000 D
Stock Option (right to buy) $50.02 04/04/2011 D 20,000 04/16/2001(2) 04/16/2011 Genzyme common stock (GENZ) 20,000 $50.02 0.0000 D
Stock Option (right to buy) $58.66 04/04/2011 D 42,750 05/21/2009(2) 05/21/2019 Genzyme common stock (GENZ) 42,750 $58.66 0.0000 D
Stock Option (right to buy) $68.48 04/04/2011 D 45,000 05/22/2008(2) 05/22/2018 Genzyme common stock (GENZ) 45,000 $68.48 0.0000 D
Stock Option (right to buy) $62.16 04/04/2011 D 22,642 05/24/2007(2) 05/24/2017 Genzyme common stock (GENZ) 22,642 $62.16 0.0000 D
Stock Option (right to buy) $62.16 04/04/2011 D 1,608 05/24/2011(2) 05/24/2017 Genzyme common stock (GENZ) 1,608 $62.16 0.0000 D
Stock Option (right to buy) $58.5 04/04/2011 D 48,500 05/25/2006(2) 05/25/2016 Genzyme common stock (GENZ) 48,500 $58.5 0.0000 D
Stock Option (right to buy) $62.98 04/04/2011 D 35,000 05/26/2005(2) 05/26/2015 Genzyme common stock (GENZ) 35,000 $62.98 0.0000 D
Stock Option (right to buy) $43.9 04/04/2011 D 41,000 05/27/2004(2) 05/27/2014 Genzyme common stock (GENZ) 41,000 $43.9 0.0000 D
Stock Option (right to buy) $46.24 04/04/2011 D 22,500 05/29/2003(2) 05/29/2013 Genzyme common stock (GENZ) 22,500 $46.24 0.0000 D
Stock Option (right to buy) $32.52 04/04/2011 D 20,630 05/30/2002(2) 05/30/2012 Genzyme common stock (GENZ) 20,630 $32.52 0.0000 D
Stock Option (right to buy) $53.47 04/04/2011 D 29,080 05/31/2001(2) 05/31/2011 Genzyme common stock (GENZ) 29,080 $53.47 0.0000 D
Stock Option (right to buy) $27.46 04/04/2011 D 4,000 06/12/2002(2) 06/12/2012 Genzyme common stock (GENZ) 4,000 $27.46 0.0000 D
Explanation of Responses:
1. The vested restricted stock units were scheduled to be released on 5/22/2011 and 5/21/2012.
2. This option, which provided for vesting 20% at grant and 20% annually over four years, was cancelled upon the consummation of the sanofi-aventis tender offer in exchange for a payment representing (A) an amount of cash equal to the excess of $74.00 over the exercise price of the option, multiplied by the total number of shares subject to such options, and (B) one contingent value right (CVR) per cancelled option.
Susan P. Cogswell, Attorney-in-Fact 04/06/2011
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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