As Filed with the Securities and Exchange Commission on November 15, 2010

Registration No. 333-132484

Registration No. 333-132484-01

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

POST-EFFECTIVE AMENDMENT NO. 5 TO FORM S-1

ON FORM S-3

REGISTRATION STATEMENT

UNDER

THE SECURITIES ACT OF 1933

POWERSHARES DB G10 CURRENCY HARVEST FUND

(Registrant)

DB G10 CURRENCY HARVEST MASTER FUND

(Rule 140 Co-Registrant)

(Exact name of registrant as specified in its charter)

Copies to:

Michael J. Schmidtberger, Esq.

Sidley Austin LLP

787 Seventh Avenue

New York, New York 10019

Pursuant to Item 512(a)(3) of Regulation S-K, all registered but unsold Common Units of Beneficial Interest of PowerShares DB G10 Currency Harvest Fund registered under SEC File Nos. 333-132484 and 333-132484-01 are hereby deregistered under the Securities Act of 1933 effective as of the date hereof.

II-1

SIGNATURES

Pursuant to the requirements of the Securities Act of 1933, the Managing Owner of the Registrant and Co-Registrant certifies that it has reasonable grounds to believe that the Registrant and Co-Registrant meet all of the requirements for filing on Form S-3 and have duly caused this Post-Effective Amendment No. 5 to the Registration Statement on Form S-1 on Form S-3 to be signed on their behalf by the undersigned, thereunto duly authorized, in the City of New York, and State of New York, on the 15^th day of November, 2010.

II-2