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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108   57,618,742 2,405,793 SH   SOLE   2,405,793 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106   1,349,112 160,800 SH   SOLE   160,800 0 0
ALIGN TECHNOLOGY INC COM 016255101   26,383,312 74,605 SH   SOLE   74,605 0 0
ALKERMES PLC COM G01767105   18,886,420 603,400 SH   SOLE   603,400 0 0
AMICUS THERAPEUTICS INC COM 03152W109   132,181,716 10,524,022 SH   SOLE   10,524,022 0 0
ANAPTYSBIO INC COM 032724106   8,771,096 431,224 SH   SOLE   431,224 0 0
BIOGEN INC COM 09062X103   108,608,178 381,282 SH   SOLE   381,282 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101   158,714,114 1,831,035 SH   SOLE   1,831,035 0 0
CYTOKINETICS INC COM 23282W605   3,644,209 111,717 SH   SOLE   111,717 0 0
EHEALTH INC COM 28238P109   22,024,607 2,739,379 SH   SOLE   2,739,379 0 0
GOSSAMER BIO INC COM 38341P102   4,158,182 3,465,152 SH   SOLE   3,465,152 0 0
GRITSTONE ONCOLOGY INC COM 39868T105   1,298,948 666,127 SH   SOLE   666,127 0 0
INSMED INC COM 457669307   124,268,260 5,889,491 SH   SOLE   5,889,491 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106   10,159,818 5,675,876 SH   SOLE   5,675,876 0 0
KEZAR LIFE SCIENCES INC COM 49372L100   1,607,690 656,200 SH   SOLE   656,200 0 0
MIRUM PHARMACEUTICALS INC COM 604749101   1,673,789 64,700 SH   SOLE   64,700 0 0
NEVRO CORP COM 64157F103   4,734,704 186,259 SH   SOLE   186,259 0 0
NOVOCURE LTD COM G6674U108   23,991,897 578,118 SH   SOLE   578,118 0 0
PROTHENA CORP PLC COM G72800108   113,171,232 1,657,458 SH   SOLE   1,657,458 0 0
RELMADA THERAPEUTICS INC COM 75955J402   1,801,704 732,400 SH   SOLE   732,400 0 0
REVANCE THERAPEUTICS INC COM 761330109   132,336,094 5,228,609 SH   SOLE   5,228,609 0 0
SAGE THERAPEUTICS INC COM 78667J108   40,414,489 859,517 SH   SOLE   859,517 0 0
SAREPTA THERAPEUTICS INC COM 803607100   10,768,316 94,030 SH   SOLE   94,030 0 0
STAAR SURGICAL CO COM 852312305   72,274,393 1,374,822 SH   SOLE   1,374,822 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   12,821,718 612,600 SH   SOLE   612,600 0 0
TACTILE SYSTEMS TECHNOLOGY I COM 87357P100   675,603 27,100 SH   SOLE   27,100 0 0
TRAVERE THERAPEUTICS INC COM 89422G107   2,550,820 166,069 SH   SOLE   166,069 0 0
UNITED THERAPEUTICS CORP COM 91307C102   138,523,716 627,514 SH   SOLE   627,514 0 0
UROGEN PHARMA LTD COM M96088105   253,575 24,500 SH   SOLE   24,500 0 0
VANDA PHARMACEUTICALS INC COM 921659108   2,135,641 324,073 SH   SOLE   324,073 0 0