The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COM 002824100   25,179,054 230,958 SH   SOLE 1 127,604 0 103,354
ABBOTT LABS COM 002824100   2,076,831 19,050 SH   OTR   19,050 0 0
ACCENTURE PLC IRELAND SHS CLASS A G1151C101   27,284,644 88,420 SH   SOLE 1 43,129 0 45,291
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109   20,334,769 3,030,517 SH   SOLE 1 1,338,618 0 1,691,899
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109   499,519 74,444 SH   OTR   74,444 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101   2,444,950 5,000 SH   OTR   5,000 0 0
ALEXANDRIA REAL ESTATE EQ IN COM 015271109   9,146,613 80,594 SH   SOLE 1 47,694 0 32,900
ALEXANDRIA REAL ESTATE EQ IN COM 015271109   2,951 26 SH   OTR   26 0 0
ALPHABET INC CAP STK CL C 02079K107   18,157,718 150,101 SH   SOLE 1 13,997 0 136,104
ALPHABET INC CAP STK CL A 02079K305   103,399,493 863,822 SH   SOLE 1 380,468 0 483,354
ALPHABET INC CAP STK CL A 02079K305   40,578 339 SH   OTR   339 0 0
AMAZON COM INC COM 023135106   67,876,757 520,687 SH   SOLE 1 331,192 0 189,495
AMAZON COM INC COM 023135106   1,819,565 13,958 SH   OTR   13,958 0 0
AMERICAN TOWER CORP NEW COM 03027X100   7,757,600 40,000 SH   OTR   40,000 0 0
AMERICAN WTR WKS CO INC NEW COM 030420103   8,144,084 57,051 SH   SOLE 1 54,149 0 2,902
AMERICAN WTR WKS CO INC NEW COM 030420103   256,950 1,800 SH   OTR   1,800 0 0
AMERIPRISE FINL INC COM 03076C106   25,782,673 77,621 SH   SOLE 1 45,686 0 31,935
AMERIPRISE FINL INC COM 03076C106   8,968 27 SH   OTR   27 0 0
AMETEK INC COM 031100100   23,319,962 144,057 SH   SOLE 1 138,192 0 5,865
AMETEK INC COM 031100100   19,638,796 121,317 SH   OTR   121,317 0 0
ANTERO RESOURCES CORP COM 03674X106   6,145,786 266,860 SH   SOLE 1 252,879 0 13,981
APPLE INC COM 037833100   227,491,251 1,172,816 SH   SOLE 1 460,994 0 711,822
APPLE INC COM 037833100   4,937,894 25,457 SH   OTR   25,457 0 0
APPLIED MATLS INC COM 038222105   16,644,070 115,152 SH   SOLE 1 50,541 0 64,611
AVERY DENNISON CORP COM 053611109   16,999,451 98,949 SH   SOLE 1 68,555 0 30,394
BANK AMERICA CORP COM 060505104   8,591,995 299,477 SH   SOLE 1 284,214 0 15,263
BECTON DICKINSON & CO COM 075887109   34,699,923 131,434 SH   SOLE 1 67,664 0 63,770
BIOMARIN PHARMACEUTICAL INC COM 09061G101   1,901,759 21,940 SH   SOLE 1 21,940 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101   89,454 1,032 SH   OTR   1,032 0 0
BIO-TECHNE CORP COM 09073M104   46,333,678 567,606 SH   SOLE 1 201,849 0 365,757
BIO-TECHNE CORP COM 09073M104   7,722,851 94,608 SH   OTR   94,608 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108   10,497,904 164,158 SH   SOLE 1 155,836 0 8,322
BRISTOL-MYERS SQUIBB CO COM 110122108   4,323,020 67,600 SH   OTR   67,600 0 0
BROADCOM INC COM 11135F101   33,017,037 38,063 SH   SOLE 1 20,553 0 17,510
BROADCOM INC COM 11135F101   1,648,117 1,900 SH   OTR   1,900 0 0
CHART INDS INC COM 16115Q308   23,860,003 149,321 SH   SOLE 1 67,873 0 81,448
CHART INDS INC COM 16115Q308   229,458 1,436 SH   OTR   1,436 0 0
CHUBB LIMITED COM H1467J104   26,787,655 139,113 SH   SOLE 1 74,202 0 64,911
COCA COLA CO COM 191216100   843,080 14,000 SH   OTR   14,000 0 0
CONSTELLATION BRANDS INC CL A 21036P108   1,796,995 7,301 SH   SOLE 1 7,301 0 0
CONSTELLATION BRANDS INC CL A 21036P108   200,842 816 SH   OTR   816 0 0
COOPER COS INC COM NEW 216648402   6,134,880 16,000 SH   OTR   16,000 0 0
COSTCO WHSL CORP NEW COM 22160K105   46,210,801 85,833 SH   SOLE 1 35,627 0 50,206
COSTCO WHSL CORP NEW COM 22160K105   681,051 1,265 SH   OTR   1,265 0 0
CROWDSTRIKE HLDGS INC CL A 22788C105   18,491,520 125,904 SH   SOLE 1 20,704 0 105,200
CROWDSTRIKE HLDGS INC CL A 22788C105   476,446 3,244 SH   OTR   3,244 0 0
DANAHER CORPORATION COM 235851102   240,000 1,000 SH   OTR   1,000 0 0
DARLING INGREDIENTS INC COM 237266101   58,082,454 910,526 SH   SOLE 1 295,737 0 614,789
DARLING INGREDIENTS INC COM 237266101   60,983 956 SH   OTR   956 0 0
DEXCOM INC COM 252131107   25,982,537 202,183 SH   SOLE 1 43,083 0 159,100
DEXCOM INC COM 252131107   11,694 91 SH   OTR   91 0 0
DOLLAR GEN CORP NEW COM 256677105   5,914,117 34,834 SH   SOLE 1 33,059 0 1,775
DOLLAR GEN CORP NEW COM 256677105   5,433 32 SH   OTR   32 0 0
DOVER CORP COM 260003108   206,710 1,400 SH   OTR   1,400 0 0
ENERGY RECOVERY INC COM 29270J100   419,250 15,000 SH   OTR   15,000 0 0
ENPHASE ENERGY INC COM 29355A107   841,252 5,023 SH   SOLE 1 5,023 0 0
ENPHASE ENERGY INC COM 29355A107   1,675 10 SH   OTR   10 0 0
EXPEDIA GROUP INC COM NEW 30212P303   34,398,572 314,458 SH   SOLE 1 89,972 0 224,486
EXPEDIA GROUP INC COM NEW 30212P303   95,279 871 SH   OTR   871 0 0
EXXON MOBIL CORP COM 30231G102   27,400,445 255,482 SH   OTR   255,482 0 0
GENERAL MTRS CO COM 37045V100   21,777,300 564,764 SH   SOLE 1 275,701 0 289,063
GUARDANT HEALTH INC COM 40131M109   29,148,539 814,205 SH   SOLE 1 319,505 0 494,700
GUARDANT HEALTH INC COM 40131M109   1,552,395 43,363 SH   OTR   43,363 0 0
HALLIBURTON CO COM 406216101   8,636,054 261,777 SH   SOLE 1 248,427 0 13,350
HOME DEPOT INC COM 437076102   58,091,910 187,007 SH   SOLE 1 64,350 0 122,657
HOME DEPOT INC COM 437076102   745,536 2,400 SH   OTR   2,400 0 0
HONEYWELL INTL INC COM 438516106   15,444,497 74,431 SH   SOLE 1 71,535 0 2,896
HONEYWELL INTL INC COM 438516106   459,198 2,213 SH   OTR   2,213 0 0
IDEXX LABS INC COM 45168D104   15,369,242 30,602 SH   SOLE 1 5,802 0 24,800
IDEXX LABS INC COM 45168D104   6,384,348 12,712 SH   OTR   12,712 0 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104   26,404,899 233,506 SH   SOLE 1 113,038 0 120,468
INTERNATIONAL BUSINESS MACHS COM 459200101   321,144 2,400 SH   OTR   2,400 0 0
INTERNATIONAL FLAVORS&FRAGRA COM 459506101   1,310,529 16,466 SH   OTR   16,466 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100   8,481,764 1,204,796 SH   SOLE 1 200,796 0 1,004,000
IOVANCE BIOTHERAPEUTICS INC COM 462260100   93,132 13,229 SH   OTR   13,229 0 0
JOHNSON & JOHNSON COM 478160104   248,280 1,500 SH   OTR   1,500 0 0
JPMORGAN CHASE & CO COM 46625H100   35,380,426 243,264 SH   SOLE 1 122,297 0 120,967
JPMORGAN CHASE & CO COM 46625H100   13,392,115 92,080 SH   OTR   92,080 0 0
KLA CORP COM NEW 482480100   19,504,109 40,213 SH   SOLE 1 9,713 0 30,500
KLA CORP COM NEW 482480100   10,185 21 SH   OTR   21 0 0
LAUDER ESTEE COS INC CL A 518439104   17,610,987 89,678 SH   SOLE 1 41,798 0 47,880
LAUDER ESTEE COS INC CL A 518439104   5,106 26 SH   OTR   26 0 0
LILLY ELI & CO COM 532457108   234,490 500 SH   OTR   500 0 0
LOCKHEED MARTIN CORP COM 539830109   690,570 1,500 SH   OTR   1,500 0 0
MARRIOTT INTL INC NEW CL A 571903202   21,942,899 119,456 SH   SOLE 1 54,003 0 65,453
MERCK & CO INC COM 58933Y105   60,788,606 526,810 SH   OTR   526,810 0 0
MICROCHIP TECHNOLOGY INC. COM 595017104   6,409,388 71,541 SH   SOLE 1 67,898 0 3,643
MICROSOFT CORP COM 594918104   247,678,537 727,311 SH   SOLE 1 271,644 0 455,667
MICROSOFT CORP COM 594918104   17,625,669 51,758 SH   OTR   51,758 0 0
MURPHY OIL CORP COM 626717102   9,630,727 251,455 SH   OTR   251,455 0 0
MURPHY USA INC COM 626755102   12,728,443 40,913 SH   OTR   40,913 0 0
NETFLIX INC COM 64110L106   31,911,739 72,446 SH   SOLE 1 21,504 0 50,942
NEXTERA ENERGY INC COM 65339F101   24,040,842 324,000 SH   SOLE 1 138,596 0 185,404
NORFOLK SOUTHN CORP COM 655844108   49,583,865 218,662 SH   SOLE 1 80,776 0 137,886
NORFOLK SOUTHN CORP COM 655844108   7,937 35 SH   OTR   35 0 0
NORTHROP GRUMMAN CORP COM 666807102   856,904 1,880 SH   OTR   1,880 0 0
NVIDIA CORPORATION COM 67066G104   122,142,376 288,739 SH   SOLE 1 98,517 0 190,222
NVIDIA CORPORATION COM 67066G104   24,088,028 56,943 SH   OTR   56,943 0 0
NXP SEMICONDUCTORS N V COM N6596X109   11,836,644 57,830 SH   SOLE 1 10,130 0 47,700
NXP SEMICONDUCTORS N V COM N6596X109   10,234 50 SH   OTR   50 0 0
ON SEMICONDUCTOR CORP COM 682189105   17,695,823 187,099 SH   SOLE 1 34,499 0 152,600
ON SEMICONDUCTOR CORP COM 682189105   6,904 73 SH   OTR   73 0 0
OREILLY AUTOMOTIVE INC COM 67103H107   28,729,692 30,074 SH   SOLE 1 16,526 0 13,548
OREILLY AUTOMOTIVE INC COM 67103H107   13,374 14 SH   OTR   14 0 0
ORGANON & CO COMMON STOCK 68622V106   903,799 43,431 SH   OTR   43,431 0 0
PALO ALTO NETWORKS INC COM 697435105   843,183 3,300 SH   OTR   3,300 0 0
PARKER-HANNIFIN CORP COM 701094104   10,921,120 28,000 SH   OTR   28,000 0 0
PEPSICO INC COM 713448108   19,721,721 106,477 SH   SOLE 1 46,429 0 60,048
POTLATCHDELTIC CORPORATION COM 737630103   8,015,284 151,661 SH   OTR   151,661 0 0
PROCTER AND GAMBLE CO COM 742718109   1,019,693 6,720 SH   OTR   6,720 0 0
PROLOGIS INC. COM 74340W103   36,545,300 298,012 SH   SOLE 1 56,222 0 241,790
PROLOGIS INC. COM 74340W103   187,501 1,529 SH   OTR   1,529 0 0
QUALCOMM INC COM 747525103   357,120 3,000 SH   OTR   3,000 0 0
QUANTA SVCS INC COM 74762E102   3,091,730 15,738 SH   SOLE 1 15,738 0 0
QUANTA SVCS INC COM 74762E102   8,054 41 SH   OTR   41 0 0
ROPER TECHNOLOGIES INC COM 776696106   6,348,483 13,204 SH   SOLE   0 0 13,204
ROPER TECHNOLOGIES INC COM 776696106   17,010,704 35,380 SH   OTR   35,380 0 0
S&P GLOBAL INC COM 78409V104   33,838,724 84,409 SH   SOLE 1 7,994 0 76,415
S&P GLOBAL INC COM 78409V104   1,499,329 3,740 SH   OTR   3,740 0 0
SAGE THERAPEUTICS INC COM 78667J108   8,352,257 177,632 SH   SOLE 1 43,732 0 133,900
SAGE THERAPEUTICS INC COM 78667J108   940,118 19,994 SH   OTR   19,994 0 0
SALESFORCE INC COM 79466L302   316,890 1,500 SH   OTR   1,500 0 0
SERVICENOW INC COM 81762P102   53,416,372 95,052 SH   SOLE 1 35,719 0 59,333
SERVICENOW INC COM 81762P102   2,959,896 5,267 SH   OTR   5,267 0 0
SPIRIT AEROSYSTEMS HLDGS INC COM CL A 848574109   5,046,250 172,876 SH   SOLE 1 164,071 0 8,805
SPX TECHNOLOGIES INC COM 78473E103   241,485 2,842 SH   OTR   2,842 0 0
SYNOPSYS INC COM 871607107   49,140,808 112,861 SH   SOLE 1 33,891 0 78,970
SYNOPSYS INC COM 871607107   12,191 28 SH   OTR   28 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109   5,434,913 36,932 SH   SOLE 1 36,932 0 0
TE CONNECTIVITY LTD SHS H84989104   2,803,200 20,000 SH   OTR   20,000 0 0
TELEFLEX INCORPORATED COM 879369106   19,791,528 81,773 SH   SOLE 1 40,233 0 41,540
TELEFLEX INCORPORATED COM 879369106   1,355,368 5,600 SH   OTR   5,600 0 0
TENABLE HLDGS INC COM 88025T102   3,224,442 74,040 SH   SOLE 1 74,040 0 0
TENABLE HLDGS INC COM 88025T102   6,837 157 SH   OTR   157 0 0
TESLA INC COM 88160R101   28,075,356 107,252 SH   SOLE 1 14,752 0 92,500
THE CIGNA GROUP COM 125523100   31,499,035 112,256 SH   SOLE 1 55,056 0 57,200
THE CIGNA GROUP COM 125523100   79,971 285 SH   OTR   285 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102   36,521,465 69,998 SH   SOLE 1 29,583 0 40,415
THERMO FISHER SCIENTIFIC INC COM 883556102   22,821,867 43,741 SH   OTR   43,741 0 0
TRANE TECHNOLOGIES PLC SHS G8994E103   49,704,075 259,877 SH   SOLE 1 53,033 0 206,844
TWILIO INC CL A 90138F102   254,480 4,000 SH   OTR   4,000 0 0
UNION PAC CORP COM 907818108   19,305,897 94,350 SH   OTR   94,350 0 0
UNITEDHEALTH GROUP INC COM 91324P102   34,791,607 72,386 SH   SOLE 1 15,086 0 57,300
UNITEDHEALTH GROUP INC COM 91324P102   9,132 19 SH   OTR   19 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100   3,385,726 9,621 SH   SOLE 1 9,621 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100   7,390 21 SH   OTR   21 0 0
VISA INC COM CL A 92826C839   86,460,575 364,075 SH   SOLE 1 101,357 0 262,718
VISA INC COM CL A 92826C839   2,280,045 9,601 SH   OTR   9,601 0 0
WEC ENERGY GROUP INC COM 92939U106   700,714 7,941 SH   OTR   7,941 0 0
ZOETIS INC CL A 98978V103   13,461,656 78,170 SH   SOLE 1 38,822 0 39,348