The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | |||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | ||||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | (to the nearest dollar) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2SEVENTY BIO INC | COMMON STOCK | 901384107 | BBG00YV1J631 | 8,622,311 | 852,007 | SH | DFND | 852,007 | 0 | 0 | ||
| ACELYRIN INC | COM | 00445A100 | 55,673,548 | 2,663,806 | SH | DFND | 2,663,806 | 0 | 0 | |||
| BLACK DIAMOND THERAPEUTICS I | COM | 09203E105 | BBG00MS4Y0X8 | 3,787,500 | 750,000 | SH | DFND | 750,000 | 0 | 0 | ||
| COMPASS THERAPEUTICS INC | COM | 20454B104 | BBG00LPXKF34 | 8,998,484 | 2,829,712 | SH | DFND | 2,829,712 | 0 | 0 | ||
| CORVUS PHARMACEUTICALS INC | COM | 221015100 | BBG009F0TGJ6 | 458,000 | 200,000 | SH | DFND | 200,000 | 0 | 0 | ||
| CULLINAN ONCOLOGY INC | COM | 230031106 | BBG00HW2DGR3 | 36,736,673 | 3,414,189 | SH | DFND | 3,414,189 | 0 | 0 | ||
| DIREXION SHS ETF TR | DAILY S&P BIOTEC | 25460G716 | BBG0099SHGK3 | 4,670,250 | 325,000 | SH | DFND | 325,000 | 0 | 0 | ||
| DISC MEDICINE INC | COM | 254604101 | BBG00W9MJL04 | 5,556,172 | 125,139 | SH | DFND | 125,139 | 0 | 0 | ||
| FREELINE THERAPEUTICS HLDGS | SPONSORED ADS | 35655L206 | BBG00W5FT5H9 | 55,898 | 25,999 | SH | DFND | 25,999 | 0 | 0 | ||
| GRAPHITE BIO INC | COM | 38870X104 | BBG00XDH4P05 | 600,439 | 230,938 | SH | DFND | 230,938 | 0 | 0 | ||
| HOOKIPA PHARMA INC | COM | 43906K100 | BBG00NGMNKS3 | 694,091 | 788,740 | SH | DFND | 788,740 | 0 | 0 | ||
| IKENA ONCOLOGY INC | COM | 45175G108 | BBG00XZY4TH8 | 13,920,582 | 2,122,040 | SH | DFND | 2,122,040 | 0 | 0 | ||
| INOZYME PHARMA INC | COM | 45790W108 | BBG00J7QJMD0 | 6,656,301 | 1,195,027 | SH | DFND | 1,195,027 | 0 | 0 | ||
| KEROS THERAPEUTICS INC | COM | 492327101 | BBG00H1HP9H8 | 16,157,101 | 402,118 | SH | DFND | 402,118 | 0 | 0 | ||
| LARIMAR THERAPEUTICS INC | COM | 517125100 | BBG001V0GD97 | 8,720,383 | 3,414,468 | SH | DFND | 3,414,468 | 0 | 0 | ||
| OMEGA THERAPEUTICS INC | COMMON STOCK | 68217N105 | BBG00WCNQZQ1 | 5,912,938 | 1,055,882 | SH | DFND | 1,055,882 | 0 | 0 | ||
| ORCHARD THERAPEUTICS PLC | SPON ADS NEW | 68570P200 | BBG00M62QW74 | 3,937,394 | 2,518,181 | SH | DFND | 2,518,181 | 0 | 0 | ||
| OVID THERAPEUTICS INC | COM | 690469101 | BBG009F0TD85 | 2,836,616 | 864,822 | SH | DFND | 864,822 | 0 | 0 | ||
| PLIANT THERAPEUTICS INC | COM | 729139105 | BBG00C8083P2 | 56,480,348 | 3,117,017 | SH | DFND | 3,117,017 | 0 | 0 | ||
| PLIANT THERAPEUTICS INC | COM | 729139105 | BBG00C8083P2 | 161,828 | 130,300 | SH | Call | DFND | 130,300 | 0 | 0 | |
| PRECISION BIOSCIENCES INC | COM | 74019P108 | BBG008NSBPW2 | 843,471 | 1,603,557 | SH | DFND | 1,603,557 | 0 | 0 | ||
| RALLYBIO CORP | COM | 75120L100 | BBG011PFKG07 | 3,072,101 | 542,774 | SH | DFND | 542,774 | 0 | 0 | ||
| REPARE THERAPEUTICS INC | COM | 760273102 | BBG00V5N3XG2 | 31,726,606 | 2,998,734 | SH | DFND | 2,998,734 | 0 | 0 | ||
| SYROS PHARMACEUTICALS INC | COM NEW | 87184Q206 | BBG004FFTL85 | 2,417,452 | 767,445 | SH | DFND | 767,445 | 0 | 0 | ||
| ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 | BBG001V2MJJ2 | 3,921,050 | 85,000 | SH | DFND | 85,000 | 0 | 0 | ||
| VECTIVBIO HLDG AG | ORD SHS | H9060V101 | BBG00ZR8HCJ0 | 46,945,093 | 2,782,756 | SH | DFND | 2,782,756 | 0 | 0 | ||