The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108   45,277,024 2,405,793 SH   SOLE   2,405,793 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106   1,596,744 160,800 SH   SOLE   160,800 0 0
ALIGN TECHNOLOGY INC COM 016255101   24,928,515 74,605 SH   SOLE   74,605 0 0
ALKERMES PLC COM G01767105   17,009,846 603,400 SH   SOLE   603,400 0 0
AMICUS THERAPEUTICS INC COM 03152W109   116,711,404 10,524,022 SH   SOLE   10,524,022 0 0
ANAPTYSBIO INC COM 032724106   9,383,434 431,224 SH   SOLE   431,224 0 0
BIOGEN INC COM 09062X103   106,007,834 381,282 SH   SOLE   381,282 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101   178,049,843 1,831,035 SH   SOLE   1,831,035 0 0
CYTOKINETICS INC COM 23282W605   3,931,321 111,717 SH   SOLE   111,717 0 0
EHEALTH INC COM 28238P109   25,172,587 2,689,379 SH   SOLE   2,689,379 0 0
GOSSAMER BIO INC COM 38341P102   4,366,092 3,465,152 SH   SOLE   3,465,152 0 0
GRITSTONE ONCOLOGY INC COM 39868T105   1,851,833 666,127 SH   SOLE   666,127 0 0
INSMED INC COM 457669307   100,415,822 5,889,491 SH   SOLE   5,889,491 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106   22,079,158 5,675,876 SH   SOLE   5,675,876 0 0
KEZAR LIFE SCIENCES INC COM 49372L100   2,053,906 656,200 SH   SOLE   656,200 0 0
MIRUM PHARMACEUTICALS INC COM 604749101   1,554,094 64,700 SH   SOLE   64,700 0 0
NOVOCURE LTD COM G6674U108   1,971,991 32,790 SH   SOLE   32,790 0 0
PEAK BIO INC COM 70470P108   314,141 497,528 SH   SOLE   497,528 0 0
PROTHENA CORP PLC COM G72800108   80,643,271 1,663,777 SH   SOLE   1,663,777 0 0
PROVENTION BIO INC COM 74374N102   9,418,280 390,800 SH   SOLE   390,800 0 0
RELMADA THERAPEUTICS INC COM 75955J402   1,225,146 542,100 SH   SOLE   542,100 0 0
REVANCE THERAPEUTICS INC COM 761330109   169,753,432 5,270,209 SH   SOLE   5,270,209 0 0
SAGE THERAPEUTICS INC COM 78667J108   36,065,333 859,517 SH   SOLE   859,517 0 0
STAAR SURGICAL CO COM 852312305   86,161,242 1,347,322 SH   SOLE   1,347,322 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   12,938,112 612,600 SH   SOLE   612,600 0 0
TACTILE SYSTEMS TECHNOLOGY I COM 87357P100   444,982 27,100 SH   SOLE   27,100 0 0
TRAVERE THERAPEUTICS INC COM 89422G107   3,734,892 166,069 SH   SOLE   166,069 0 0
UNITED THERAPEUTICS CORP COM 91307C102   140,538,035 627,514 SH   SOLE   627,514 0 0
UROGEN PHARMA LTD COM M96088105   226,380 24,500 SH   SOLE   24,500 0 0
VANDA PHARMACEUTICALS INC COM 921659108   3,277,513 482,697 SH   SOLE   482,697 0 0