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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ALECTOR INC COM 014442107   2,101,932 339,569 SH   DFND   339,569 0 0
AMRYT PHARMA PLC SPONSORED ADS 03217L106   6,557,165 449,737 SH   DFND   449,737 0 0
ARAVIVE INC COM 03890D108   1,892,846 946,423 SH   DFND   946,423 0 0
ARVINAS INC COM 04335A105   35,229,714 1,289,521 SH   DFND   1,289,521 0 0
AVROBIO INC COM 05455M100   315,550 315,550 SH   DFND   315,550 0 0
CHIMERIX INC COM 16934W106   1,542,996 1,224,600 SH   DFND   1,224,600 0 0
COGENT BIOSCIENCES INC. COM 19240Q201   5,411,509 501,530 SH   DFND   501,530 0 0
CRINETICS PHARMACEUTICALS INC COM 22663K107   2,264,460 141,000 SH   DFND   141,000 0 0
DECIPHERA PHARMACEUTICALS INC COM 24344T101   18,687,872 1,209,571 SH   DFND   1,209,571 0 0
DICE THERAPEUTICS INC COM 23345J104   10,649,004 371,693 SH   DFND   371,693 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105   10,362,919 1,553,661 SH   DFND   1,553,661 0 0
HARPOON THERAPEUTICS INC COM 41358P106   2,335,957 3,156,699 SH   DFND   3,156,699 0 0
ITERUM THERAPEUTICS PLC SHS G6333L200   97,084 97,084 SH   DFND   97,084 0 0
PASSAGE BIO COM 702712100   2,398,005 2,497,922 SH   DFND   2,497,922 0 0
RALLYBIO CORPORATION COM 75120L100   18,852,153 3,301,603 SH   DFND   3,301,603 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106   2,025,485 118,242 SH   DFND   118,242 0 0
X4 PHARMACEUTICALS INC COM 98420X103   291,450 335,000 SH   DFND   335,000 0 0